On 2014 May 05, Martine Crasnier-Mednansky commented:

Data by Wanner BL, 1978 did not indicate β-galactosidase activity is inversely proportional to the specific growth rate. In fact, data from Wanner Figure 1A indicated a large variation in β-galactosidase activity occurred in media supporting similar growth rate (thus synthesis rate is not constant). In addition, data from Wanner Figure 2B did not indicate addition of exogenous cAMP increased β-galactosidase activities less than two-fold. Wanner et al. stated "Media in which there was marked growth rate inhibition by cAMP also showed large stimulation of β-galactosidase synthesis; a growth rate inhibition, however, was not a necessary condition for an increase in the enzyme activity". In the presence of cAMP however, even though much of the variation was eliminated, repression remained which was carbon source dependent and growth related. Whether it [the remaining repression] is mediated by cAMP is uncertain - concluded Wanner et al.

On 2014 May 05, Martine Crasnier-Mednansky commented:

Data by Wanner BL, 1978 did not indicate β-galactosidase activity is inversely proportional to the specific growth rate. In fact, data from Wanner Figure 1A indicated a large variation in β-galactosidase activity occurred in media supporting similar growth rate (thus synthesis rate is not constant). In addition, data from Wanner Figure 2B did not indicate addition of exogenous cAMP increased β-galactosidase activities less than two-fold. Wanner et al. stated "Media in which there was marked growth rate inhibition by cAMP also showed large stimulation of β-galactosidase synthesis; a growth rate inhibition, however, was not a necessary condition for an increase in the enzyme activity". In the presence of cAMP however, even though much of the variation was eliminated, repression remained which was carbon source dependent and growth related. Whether it [the remaining repression] is mediated by cAMP is uncertain - concluded Wanner et al.