2 Matching Annotations
  1. Jul 2018
    1. On 2016 Aug 08, Stuart RAY commented:

      The single line "Erratum in Correction [Hepatology. 2015]" above does not capture the complex recent history of this publication. That correction notes a 12-fold (person-years vs. person-months) calculation error that, once corrected, eliminates any statistical difference in HCC rates between those with HBsAg loss and those with HCC persistence.

      Fortunately, an alert and astute reader (Chee-Kiat Tan, Singapore General Hospital) called attention to the important implications of this error in a Letter to the Editor [which, I hope, will be linked from this Pubmed record]. The authors provided a fairly terse reply.

      In a notably rare Editorial response to Tan's letter, Michael Nathanson and Norah Terrault note that a key conclusion of the report is arguably strengthened by the correction: that HCC can occur in persons even after HBsAg loss, even in the absence of cirrhosis.

      The importance of vigilance for HCC in persons with HBV infection (even in the absence of detectable HBsAg) is amplified by this correction; careful reading of the literature is also emphasized.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

  2. Feb 2018
    1. On 2016 Aug 08, Stuart RAY commented:

      The single line "Erratum in Correction [Hepatology. 2015]" above does not capture the complex recent history of this publication. That correction notes a 12-fold (person-years vs. person-months) calculation error that, once corrected, eliminates any statistical difference in HCC rates between those with HBsAg loss and those with HCC persistence.

      Fortunately, an alert and astute reader (Chee-Kiat Tan, Singapore General Hospital) called attention to the important implications of this error in a Letter to the Editor [which, I hope, will be linked from this Pubmed record]. The authors provided a fairly terse reply.

      In a notably rare Editorial response to Tan's letter, Michael Nathanson and Norah Terrault note that a key conclusion of the report is arguably strengthened by the correction: that HCC can occur in persons even after HBsAg loss, even in the absence of cirrhosis.

      The importance of vigilance for HCC in persons with HBV infection (even in the absence of detectable HBsAg) is amplified by this correction; careful reading of the literature is also emphasized.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.