On 2017 Jan 20, Andy Collings commented:

A subset of experimental results from this study were the focus of a replication attempt as part of the Reproducibility Project: Cancer Biology (https://osf.io/e81xl/wiki/home/). The experimental designs and protocols were reviewed and approved in a Registered Report (http://dx.doi.org/10.7554/eLife.06847) and the results of the experiments were published in a Replication Study (http://dx.doi.org/10.7554/eLife.17044).

On 2013 Jun 17, Jessie Tenenbaum commented:

With the disclaimer that this came out of my PhD lab (4 years after I left), I really like this paper. I remember seeing a naysayer comment (on GenomeWeb maybe?) questioning whether this belonged in STM, but this is exactly what big data mining approaches is meant to do- yes, it's about hypothesis generation, but if those hypotheses can then be validated in a model system, trimming years off the drug discovery process, that is truly impactful.

On 2013 Jun 17, Jessie Tenenbaum commented:

With the disclaimer that this came out of my PhD lab (4 years after I left), I really like this paper. I remember seeing a naysayer comment (on GenomeWeb maybe?) questioning whether this belonged in STM, but this is exactly what big data mining approaches is meant to do- yes, it's about hypothesis generation, but if those hypotheses can then be validated in a model system, trimming years off the drug discovery process, that is truly impactful.

On 2017 Jan 20, Andy Collings commented:

A subset of experimental results from this study were the focus of a replication attempt as part of the Reproducibility Project: Cancer Biology (https://osf.io/e81xl/wiki/home/). The experimental designs and protocols were reviewed and approved in a Registered Report (http://dx.doi.org/10.7554/eLife.06847) and the results of the experiments were published in a Replication Study (http://dx.doi.org/10.7554/eLife.17044).