On 2013 Jun 15, Steven Salzberg commented:

This is a very cool result. All of our techniques for sequencing transcripts and then assembling them into genes assume the result should be a linear molecule. By relaxing this assumption, Salzman and colleagues found large numbers of RNAs that appear to be circular. It's a whole new model that raises several intriguing new questions: are these translated, and if so how easily? Do they survive longer due to their circularity?

On 2013 Jun 15, Steven Salzberg commented:

This is a very cool result. All of our techniques for sequencing transcripts and then assembling them into genes assume the result should be a linear molecule. By relaxing this assumption, Salzman and colleagues found large numbers of RNAs that appear to be circular. It's a whole new model that raises several intriguing new questions: are these translated, and if so how easily? Do they survive longer due to their circularity?