2 Matching Annotations
  1. Jul 2018
    1. On 2016 May 24, Kevin Hall commented:

      A Corrigendum for this article (10.1210/jc.2012-1444) was published on May 10, 2016: http://dx.doi.org/10.1210/jc.2016-1651.

      We recently identified an error in the week 30 resting metabolic rate (RMR) data in the above manuscript. In Table 1, the RMR at week 30 in the full 16 subject sample was (mean ±SD) 2015 ±332 kcal/d such that there was a decrease from baseline of 664 ± 469 kcal/d (p<0.0001) with a significant metabolic adaptation of -370 ± 290 kcal/d (p<0.0001). Also in Table 1, the week 30 RMR of the 11 subjects completing measurements at 6 weeks was 1926 ± 328 kcal/d (p=0.001 vs. baseline) and the metabolic adaptation of -345 ± 239 kcal/d (p=0.0004) was no longer significantly different from week 6 (p=0.082). A corrected Figure 2 was published in the Corrigendum.

      In Figure 3A, non-resting energy expenditure at week 30 was 1129 ±399 kcal/d and significantly lower than baseline (p=0.04). Physical activity at week 30 shown in Figure 3B was 4.4 ±3.3 kcal/kg/d higher than baseline (p < 0.0001) and significantly lower than week 6 (p =0.02). The previously reported correlation of metabolic adaptation with weight loss at week 30 remained significant (r=0.56, p=0.038) but the correlation with TSH change was no longer significant (r=0.16, p=0.61). The authors regret this error.


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  2. Feb 2018
    1. On 2016 May 24, Kevin Hall commented:

      A Corrigendum for this article (10.1210/jc.2012-1444) was published on May 10, 2016: http://dx.doi.org/10.1210/jc.2016-1651.

      We recently identified an error in the week 30 resting metabolic rate (RMR) data in the above manuscript. In Table 1, the RMR at week 30 in the full 16 subject sample was (mean ±SD) 2015 ±332 kcal/d such that there was a decrease from baseline of 664 ± 469 kcal/d (p<0.0001) with a significant metabolic adaptation of -370 ± 290 kcal/d (p<0.0001). Also in Table 1, the week 30 RMR of the 11 subjects completing measurements at 6 weeks was 1926 ± 328 kcal/d (p=0.001 vs. baseline) and the metabolic adaptation of -345 ± 239 kcal/d (p=0.0004) was no longer significantly different from week 6 (p=0.082). A corrected Figure 2 was published in the Corrigendum.

      In Figure 3A, non-resting energy expenditure at week 30 was 1129 ±399 kcal/d and significantly lower than baseline (p=0.04). Physical activity at week 30 shown in Figure 3B was 4.4 ±3.3 kcal/kg/d higher than baseline (p < 0.0001) and significantly lower than week 6 (p =0.02). The previously reported correlation of metabolic adaptation with weight loss at week 30 remained significant (r=0.56, p=0.038) but the correlation with TSH change was no longer significant (r=0.16, p=0.61). The authors regret this error.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.