2 Matching Annotations
  1. Jul 2018
    1. On 2013 Nov 03, Dale D O Martin commented:

      In Figure 2, amino acids 512, 552 and 586 should be listed as caspase cleavage sites, not phosphorylation sites, and should be aspartate residues, not serines.

      Caspase cleavage of HTT is reviewed here: http://www.ncbi.nlm.nih.gov/pubmed/21311053

      These sites are well established as caspase cleavage sites and are also listed on the Human protein resource database here: http://www.hprd.org/summary?hprd_id=00883&isoform_id=00883_1&isoform_name=Isoform_1


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

  2. Feb 2018
    1. On 2013 Nov 03, Dale D O Martin commented:

      In Figure 2, amino acids 512, 552 and 586 should be listed as caspase cleavage sites, not phosphorylation sites, and should be aspartate residues, not serines.

      Caspase cleavage of HTT is reviewed here: http://www.ncbi.nlm.nih.gov/pubmed/21311053

      These sites are well established as caspase cleavage sites and are also listed on the Human protein resource database here: http://www.hprd.org/summary?hprd_id=00883&isoform_id=00883_1&isoform_name=Isoform_1


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.