2 Matching Annotations
  1. Jul 2018
    1. On 2014 Jan 07, Brett Snodgrass commented:

      Dear Reader,

      Case reports may render pertinent drug safety signals, but usually do not warrant definitive conclusions.

      Contrast the findings from a case of in utero cocaine exposure, there were multiple arteries of multiple vascular beds c FMD. The focal FMD reported in this case is likely idiopathic. If amphetamine caused the vasospasm, why was the FMD focal? Since Sumatriptan causes vasospasm, then the possibility of synergy between amphetamine and sumatriptan might be considered.

      Please see the following article regarding In Utero cocaine expsoure. http://www.ncbi.nlm.nih.gov/pubmed/17868884

      For additional commentary, please see https://twitter.com/BrettSnodgrass1/status/413491218023481344

      Thank you kindly.


      Addendum: The following case report contains similar findings, but without amphetamine exposure. Please exercise caution when using a case report to create an association. http://www.ncbi.nlm.nih.gov/pubmed/17905452


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

  2. Feb 2018
    1. On 2014 Jan 07, Brett Snodgrass commented:

      Dear Reader,

      Case reports may render pertinent drug safety signals, but usually do not warrant definitive conclusions.

      Contrast the findings from a case of in utero cocaine exposure, there were multiple arteries of multiple vascular beds c FMD. The focal FMD reported in this case is likely idiopathic. If amphetamine caused the vasospasm, why was the FMD focal? Since Sumatriptan causes vasospasm, then the possibility of synergy between amphetamine and sumatriptan might be considered.

      Please see the following article regarding In Utero cocaine expsoure. http://www.ncbi.nlm.nih.gov/pubmed/17868884

      For additional commentary, please see https://twitter.com/BrettSnodgrass1/status/413491218023481344

      Thank you kindly.


      Addendum: The following case report contains similar findings, but without amphetamine exposure. Please exercise caution when using a case report to create an association. http://www.ncbi.nlm.nih.gov/pubmed/17905452


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.