On 2014 Nov 25, Harri Hemila commented:

Nakano T, 2012 reported an outbreak of tetanus in Japanese macaques (1). Monkeys and humans are unable to synthesize vitamin C and therefore it may have similar effects on both. In 1955, CHAKRABARTI B, 1955 reported that tetanus patients had lower plasma vitamin C levels than healthy controls, and tetanus patients who died had lower levels than those who survived. A controlled trial carried out in Bangladesh in the 1980s tested the effect of intravenous vitamin C on tetanus patients. Jahan K, 1984 administered 1 g/day of vitamin C to children aged 1 to 12 years and none of them died (0/31), whereas 74% (23/31) of control children died. In tetanus patients aged 13 to 30 years, 37% (10/27) of the vitamin C group died, compared with 68% (19/28) of the control group. Although the Jahan trial has methodological shortcomings, the findings should not be ignored on the basis of potential biases Hemilä H, 2013. Furthermore, in an animal study, Dey PK, 1966 reported that five rats administered twice the minimal lethal dose of tetanus toxin all died, whereas 25 rats administered vitamin C either before or after the toxin all lived. Treatment effects of vitamin C should be tested in monkeys with tetanus.

On 2014 Nov 25, Harri Hemila commented:

Nakano T, 2012 reported an outbreak of tetanus in Japanese macaques (1). Monkeys and humans are unable to synthesize vitamin C and therefore it may have similar effects on both. In 1955, CHAKRABARTI B, 1955 reported that tetanus patients had lower plasma vitamin C levels than healthy controls, and tetanus patients who died had lower levels than those who survived. A controlled trial carried out in Bangladesh in the 1980s tested the effect of intravenous vitamin C on tetanus patients. Jahan K, 1984 administered 1 g/day of vitamin C to children aged 1 to 12 years and none of them died (0/31), whereas 74% (23/31) of control children died. In tetanus patients aged 13 to 30 years, 37% (10/27) of the vitamin C group died, compared with 68% (19/28) of the control group. Although the Jahan trial has methodological shortcomings, the findings should not be ignored on the basis of potential biases Hemilä H, 2013. Furthermore, in an animal study, Dey PK, 1966 reported that five rats administered twice the minimal lethal dose of tetanus toxin all died, whereas 25 rats administered vitamin C either before or after the toxin all lived. Treatment effects of vitamin C should be tested in monkeys with tetanus.