On 2013 Jun 13, Julia Salzman commented:

This is an intriguing and provocative study especially given the excerpt below. More controls and more data would be very interesting. For example, could the authors use Sanger or NGS to show that the detected XY DNA in the maternal brain had SNPs or other markers that identified the DNA as coming from their sons?

"Regarding the relationship between pregnancy history and Mc prevalence, five of nine subjects who were known to have at least one son harbored male Mc in at least one of their brain regions (Table S3). All positive individuals had AD; among the negatives were three with AD and one without neurologic disease. One of two women without history of having sons was also positive for male Mc in her brain and without neurologic disease; the negative individual had AD."

On 2013 Jun 13, Julia Salzman commented:

This is an intriguing and provocative study especially given the excerpt below. More controls and more data would be very interesting. For example, could the authors use Sanger or NGS to show that the detected XY DNA in the maternal brain had SNPs or other markers that identified the DNA as coming from their sons?

"Regarding the relationship between pregnancy history and Mc prevalence, five of nine subjects who were known to have at least one son harbored male Mc in at least one of their brain regions (Table S3). All positive individuals had AD; among the negatives were three with AD and one without neurologic disease. One of two women without history of having sons was also positive for male Mc in her brain and without neurologic disease; the negative individual had AD."