- Jul 2018
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europepmc.org europepmc.org
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On 2013 Jun 17, John Overington commented:
Reviews and discusses two important concepts - firstly - ligand-based clustering of biological receptors on the basis of ensembles of ligands that bind to them, and then the development of an organisational framework based on these similarities; and secondly - the concept of a time domain in biological signalling and response to a given small molecule ligand - reflecting the limited repertoire of small molecule ligands and the response systems with radically different time constants.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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europepmc.org europepmc.org
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On 2013 Jun 17, John Overington commented:
Reviews and discusses two important concepts - firstly - ligand-based clustering of biological receptors on the basis of ensembles of ligands that bind to them, and then the development of an organisational framework based on these similarities; and secondly - the concept of a time domain in biological signalling and response to a given small molecule ligand - reflecting the limited repertoire of small molecule ligands and the response systems with radically different time constants.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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