- Jul 2018
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europepmc.org europepmc.org
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On 2017 Aug 05, Fernando Castro-Chavez commented:
Dear Reader, in this work I had the opportunity to use the novel technology of 3-D magnetic levitation to produce human Vascular Smooth Muscle Cells (VSMC) calcifying after the addition of Lyso Phosphatidyl Choline (LPC), it took me a couple of years to optimize every detail to obtain the most amazing images of those spherical clusters secreting the calcium Hydroxyl Apatite (HA) in an ordered and organized manner; so, we saw that the LPC (a traveler on the surface of the LDL) is the main culprit of Atherosclerosis, because it acts as detergent of the VSMC, so, actually their efforts at calcification, trans-differentiating into osteogenic cells is their strategy of survival to continue alive. The SHN3 slightly delayed the process. Att., Fernando Castro-Chavez.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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europepmc.org europepmc.org
-
On 2017 Aug 05, Fernando Castro-Chavez commented:
Dear Reader, in this work I had the opportunity to use the novel technology of 3-D magnetic levitation to produce human Vascular Smooth Muscle Cells (VSMC) calcifying after the addition of Lyso Phosphatidyl Choline (LPC), it took me a couple of years to optimize every detail to obtain the most amazing images of those spherical clusters secreting the calcium Hydroxyl Apatite (HA) in an ordered and organized manner; so, we saw that the LPC (a traveler on the surface of the LDL) is the main culprit of Atherosclerosis, because it acts as detergent of the VSMC, so, actually their efforts at calcification, trans-differentiating into osteogenic cells is their strategy of survival to continue alive. The SHN3 slightly delayed the process. Att., Fernando Castro-Chavez.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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