On 2014 Nov 24, Roger Keller Celeste commented:

If I read correctly, authors were looking for failure of implants placed after radiotherapy versus those place in bone not irradiated.

Time after radiotherapy is an important variable that was not considered. Implants placed in irradiated bone, after long time since radiotherapy, may have similar success probability to those placed in non-irradiated bone. The idea that 6 months of healing is enough may not be true.

We have conducted a similar review Claudy MP, et al. Time Interval after Radiotherapy and Dental Implant Failure: Systematic Review of Observational Studies and Meta-Analysis, but comparing implants placed in bone irradiated between 6-12 months after radiotherapy versus implants placed after 12 months.

In our finding, the difference between groups was smaller, and we also detected influence of one study in the results. We were also able to include more studies, so to assess influence of publication bias and heterogeneity. Thanks, Roger Keller Celeste, PhD in Epidemiology Federal University of Rio Grande do Sul, Brazil Faculty of Dentistry

On 2014 Nov 24, Roger Keller Celeste commented:

If I read correctly, authors were looking for failure of implants placed after radiotherapy versus those place in bone not irradiated.

Time after radiotherapy is an important variable that was not considered. Implants placed in irradiated bone, after long time since radiotherapy, may have similar success probability to those placed in non-irradiated bone. The idea that 6 months of healing is enough may not be true.

We have conducted a similar review Claudy MP, et al. Time Interval after Radiotherapy and Dental Implant Failure: Systematic Review of Observational Studies and Meta-Analysis, but comparing implants placed in bone irradiated between 6-12 months after radiotherapy versus implants placed after 12 months.

In our finding, the difference between groups was smaller, and we also detected influence of one study in the results. We were also able to include more studies, so to assess influence of publication bias and heterogeneity. Thanks, Roger Keller Celeste, PhD in Epidemiology Federal University of Rio Grande do Sul, Brazil Faculty of Dentistry