2 Matching Annotations
  1. Jul 2018
    1. On 2014 Dec 08, Rafael Najmanovich commented:

      We have recently predicted ispF to be essential in C. difficile (Larocque M, 2014). Furthermore, we built a homology model and used it to detect binding site similarities to human proteins using IsoCleft Finder (Kurbatova N, 2013). We could not find statistically significant levels of binding-site similarities to protein belonging to Pfam families that contain human homologs.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

  2. Feb 2018
    1. On 2014 Dec 08, Rafael Najmanovich commented:

      We have recently predicted ispF to be essential in C. difficile (Larocque M, 2014). Furthermore, we built a homology model and used it to detect binding site similarities to human proteins using IsoCleft Finder (Kurbatova N, 2013). We could not find statistically significant levels of binding-site similarities to protein belonging to Pfam families that contain human homologs.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.