- Jul 2018
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europepmc.org europepmc.org
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On 2014 Jun 06, Amanda Capes-Davis commented:
The authors very correctly use a panel of different cell lines to assess in vitro cytotoxic activity. Two cell lines do not come from the tissues listed; these two cell lines, HEp-2 and KB, were cross-contaminated during establishment and are actually HeLa. It is important to test cell lines for authenticity using a technique such as short tandem repeat (STR) profiling. For a list of known cross-contaminated cell lines, see http://iclac.org/databases/cross-contaminations/.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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On 2014 Jun 06, Amanda Capes-Davis commented:
The authors very correctly use a panel of different cell lines to assess in vitro cytotoxic activity. Two cell lines do not come from the tissues listed; these two cell lines, HEp-2 and KB, were cross-contaminated during establishment and are actually HeLa. It is important to test cell lines for authenticity using a technique such as short tandem repeat (STR) profiling. For a list of known cross-contaminated cell lines, see http://iclac.org/databases/cross-contaminations/.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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