- Jul 2018
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europepmc.org europepmc.org
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On 2014 May 15, Andreas R Gruber commented:
The fact that CFIm25 is a broad repressor of proximal poly(A) site usage and that knock-down of CFIm25 leads to a transcriptome-wide shortening of 3' UTRs is not novel and was first reported here:
Gruber AR, Martin G, Keller W, Zavolan M. Cleavage factor Im is a key regulator of 3' UTR length. RNA Biol. 2012 9(12):1405-12. doi: 10.4161/rna.22570
The study by Gruber et al. uses a high-quality 3'-end sequencing approach that allows direct inference of polyadenylation sites and not indirectly from less sensitive, standard RNA-seq data. The data set is publicly available in NCBI GEO: GSE40137.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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europepmc.org europepmc.org
-
On 2014 May 15, Andreas R Gruber commented:
The fact that CFIm25 is a broad repressor of proximal poly(A) site usage and that knock-down of CFIm25 leads to a transcriptome-wide shortening of 3' UTRs is not novel and was first reported here:
Gruber AR, Martin G, Keller W, Zavolan M. Cleavage factor Im is a key regulator of 3' UTR length. RNA Biol. 2012 9(12):1405-12. doi: 10.4161/rna.22570
The study by Gruber et al. uses a high-quality 3'-end sequencing approach that allows direct inference of polyadenylation sites and not indirectly from less sensitive, standard RNA-seq data. The data set is publicly available in NCBI GEO: GSE40137.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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