On 2014 Jun 28, M Felix Freshwater commented:

This "clarification" discloses a heretofore undisclosed fact. The authors now claim: "We then asked the patients whether they preferred a medical drug treatment that could decrease the libido and cause liver problems or whether they preferred to eliminate from their diet products that contained yeast, such as bread, beer, pizza, etc. The patients preferred the diet. We assert that a proposed diet does not require informed consent." The original paper made no mention of this choice. Did the authors ignore the facts that they were doing a clinical trial comparing treatment A and B, which required ethics approval or, despite their assertion that this was a prospective study, perhaps it was not. Unless the authors respond, readers will have to reach their own conclusions.

On 2014 Jun 28, M Felix Freshwater commented:

This "clarification" discloses a heretofore undisclosed fact. The authors now claim: "We then asked the patients whether they preferred a medical drug treatment that could decrease the libido and cause liver problems or whether they preferred to eliminate from their diet products that contained yeast, such as bread, beer, pizza, etc. The patients preferred the diet. We assert that a proposed diet does not require informed consent." The original paper made no mention of this choice. Did the authors ignore the facts that they were doing a clinical trial comparing treatment A and B, which required ethics approval or, despite their assertion that this was a prospective study, perhaps it was not. Unless the authors respond, readers will have to reach their own conclusions.