On 2017 Sep 22, Jan Tunér commented:

The parameters here are unclear but with the assistance of the laser manufacturer, the following calculation is made: 1. IR Source 905 nm pulsed (pulse duration = 200 ns, adjustable frequency, peak power, according to the frequency of the nominal value (45 W) 2. Continuous visible source 650 nm (output power 70 mW) The peak power (45 W nominal power) depends on the set frequency and it decreases when the frequency increases. The frequency used in the article of 30 kHz (30,000 Hz) is of about 34 Watt. The energetic value reported on the article (48.6 joule) is given from the sum of the contribution of the 2 sources: 1. Source contribution IR 905nm: 34 W200 ns30000 Hz180 sec ≈ 36 joule 2. Source contribution Visible 650nm: 0.07 W180sec = 12.6 joule The weight of a Wistar rat of 5 weeks of age is around 200 g, so a child of 10 years weighting 15 kg, in the need of PBM for the investigated condition would then receive more than 75 times 48.6 J = 3645 J. This, applied seven times during a period of two weeks, would end up in a total applied energy of 25515 J. The relevance of the reported results need to be put into that perspective.

On 2017 Sep 22, Jan Tunér commented:

The parameters here are unclear but with the assistance of the laser manufacturer, the following calculation is made: 1. IR Source 905 nm pulsed (pulse duration = 200 ns, adjustable frequency, peak power, according to the frequency of the nominal value (45 W) 2. Continuous visible source 650 nm (output power 70 mW) The peak power (45 W nominal power) depends on the set frequency and it decreases when the frequency increases. The frequency used in the article of 30 kHz (30,000 Hz) is of about 34 Watt. The energetic value reported on the article (48.6 joule) is given from the sum of the contribution of the 2 sources: 1. Source contribution IR 905nm: 34 W200 ns30000 Hz180 sec ≈ 36 joule 2. Source contribution Visible 650nm: 0.07 W180sec = 12.6 joule The weight of a Wistar rat of 5 weeks of age is around 200 g, so a child of 10 years weighting 15 kg, in the need of PBM for the investigated condition would then receive more than 75 times 48.6 J = 3645 J. This, applied seven times during a period of two weeks, would end up in a total applied energy of 25515 J. The relevance of the reported results need to be put into that perspective.