2 Matching Annotations
  1. Jul 2018
    1. On 2016 Apr 27, Nadav Sorek commented:

      After the paper was published, we became aware of anomalies in the ITC plot in figure 2, and in the gel blot presented in figure 3. I performed the experiment and prepared the figure, and was not aware of these anomalies, as they can be seen only when the contrast of the blot has been changed dramatically. The anomalies in the ITC plot were determined to have been caused by a failure in the graphics card. The reason for the anomalies in the gel blot remains unknown, although they may have occurred as a result of image compression into JPEG format. I did not retain the original uncompressed images, so this was impossible for me to resolve without repeating the experiment. I was able to demonstrate that the results reported were reproducible, however due to the anomalies, JBC insisted that we retract the paper. To remove any doubt about the reliability of the data, we asked an independent researcher to repeat the experiment, and the results from these experiments were consistent with our published results. The report with all the details can be found in bioRxiv (http://biorxiv.org/content/early/2016/04/26/050427). Please don’t hesitate to contact me with question or further clarifications.<br> Nadav Sorek (Nadav.sore.il@gmail.com)


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  2. Feb 2018
    1. On 2016 Apr 27, Nadav Sorek commented:

      After the paper was published, we became aware of anomalies in the ITC plot in figure 2, and in the gel blot presented in figure 3. I performed the experiment and prepared the figure, and was not aware of these anomalies, as they can be seen only when the contrast of the blot has been changed dramatically. The anomalies in the ITC plot were determined to have been caused by a failure in the graphics card. The reason for the anomalies in the gel blot remains unknown, although they may have occurred as a result of image compression into JPEG format. I did not retain the original uncompressed images, so this was impossible for me to resolve without repeating the experiment. I was able to demonstrate that the results reported were reproducible, however due to the anomalies, JBC insisted that we retract the paper. To remove any doubt about the reliability of the data, we asked an independent researcher to repeat the experiment, and the results from these experiments were consistent with our published results. The report with all the details can be found in bioRxiv (http://biorxiv.org/content/early/2016/04/26/050427). Please don’t hesitate to contact me with question or further clarifications.<br> Nadav Sorek (Nadav.sore.il@gmail.com)


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.