On 2015 Mar 13, Albert Erives commented:

Animal genomes do not encode the eukaryotic ClpB chaperones, Hsp104 and Hsp78 (See: Metabolic and chaperone gene loss marks the origin of animals: evidence for hsp104 and hsp78 sharing mitochondrial enzymes as clients, PMID: 25710177). The so-called CLPB gene annotated in the human genome is a partial bacterial clp family sequence fused to an ankyrin-repeat containing domain. Phylogenetic analysis of this gene from humans and other animals puts it outside of the clpB/HSP104/HSP78 family (see Fig. S2 in the above reference).

On 2015 Mar 13, Albert Erives commented:

Animal genomes do not encode the eukaryotic ClpB chaperones, Hsp104 and Hsp78 (See: Metabolic and chaperone gene loss marks the origin of animals: evidence for hsp104 and hsp78 sharing mitochondrial enzymes as clients, PMID: 25710177). The so-called CLPB gene annotated in the human genome is a partial bacterial clp family sequence fused to an ankyrin-repeat containing domain. Phylogenetic analysis of this gene from humans and other animals puts it outside of the clpB/HSP104/HSP78 family (see Fig. S2 in the above reference).