On 2015 Apr 01, Mario Capasso commented:

The authors of this meta-analysis have reported into the manuscript this sentence: "the study performed by Capasso et al Nat Genet 2009 evaluating the association between BARD1 Arg378Ser polymorphism and neuroblastoma susceptibility reported the completely opposite result compared to the study performed Capasso et al Carcinogenesis 2013. We read these two papers carefully and didn’t find the interpretation about this phenomenon by the author." This is clearly wrong. Indeed, in the two papers, we reported the frequency of the minor allele (MAF) which in the American population is G, and in the Italian population is C. In both populations, the disease associated, or risk, allele is G, with a frequency of 0.51 and 0.42 in American cases and controls, and of 0.65 and 0.52 in Italian cases and controls. Therefore, while the minor allele is different, there is no difference in the neuroblastoma risk allele, and the results are consistent in the two populations.

On 2015 Apr 01, Mario Capasso commented:

The authors of this meta-analysis have reported into the manuscript this sentence: "the study performed by Capasso et al Nat Genet 2009 evaluating the association between BARD1 Arg378Ser polymorphism and neuroblastoma susceptibility reported the completely opposite result compared to the study performed Capasso et al Carcinogenesis 2013. We read these two papers carefully and didn’t find the interpretation about this phenomenon by the author." This is clearly wrong. Indeed, in the two papers, we reported the frequency of the minor allele (MAF) which in the American population is G, and in the Italian population is C. In both populations, the disease associated, or risk, allele is G, with a frequency of 0.51 and 0.42 in American cases and controls, and of 0.65 and 0.52 in Italian cases and controls. Therefore, while the minor allele is different, there is no difference in the neuroblastoma risk allele, and the results are consistent in the two populations.