On 2015 May 07, Ryan Radecki commented:

Over 200,000 physicians belong to the American Medical Association. The Journal, therefore, of this Association has a significant audience and a long tradition. Continuing Medical Education inserts in JAMA may represent the basic education of many new developments for general practitioners.

These authors perform a systematic review on “acute stroke intervention”. They identify and review 145 abstracts utilizing multiple combinations of MeSH terms and synonyms for “brain ischemia/drug therapy, stroke drug/therapy, tissue plasminogen activator, fibrinolytic agents, endovascular procedures, thrombectomy, time factors, emergency service, treatment outcome, multicenter study, and randomized controlled trial”. A massive undertaking, to be sure – considering these authors are also including intra-arterial and mechanical therapy in their review.

Yet, as indicated in their evidence review chart in the supplement, these authors' strategy managed to identify only 17 RCTs – in the whole of systemic and endovascular therapy....

http://www.emlitofnote.com/2015/04/a-laughable-tpa-systematic-review.html

On 2015 May 07, Ryan Radecki commented:

Over 200,000 physicians belong to the American Medical Association. The Journal, therefore, of this Association has a significant audience and a long tradition. Continuing Medical Education inserts in JAMA may represent the basic education of many new developments for general practitioners.

These authors perform a systematic review on “acute stroke intervention”. They identify and review 145 abstracts utilizing multiple combinations of MeSH terms and synonyms for “brain ischemia/drug therapy, stroke drug/therapy, tissue plasminogen activator, fibrinolytic agents, endovascular procedures, thrombectomy, time factors, emergency service, treatment outcome, multicenter study, and randomized controlled trial”. A massive undertaking, to be sure – considering these authors are also including intra-arterial and mechanical therapy in their review.

Yet, as indicated in their evidence review chart in the supplement, these authors' strategy managed to identify only 17 RCTs – in the whole of systemic and endovascular therapy....

http://www.emlitofnote.com/2015/04/a-laughable-tpa-systematic-review.html