On 2015 Jun 30, Prashant Sharma, MD, DM commented:

This paper basically addresses a cost-cutting issue that sometimes unfortunately still surfaces in resource-poor settings, wherein electrophoresis-derived hemoglobin fraction percentages are used for clinical decision making.

While electrophoresis followed by elution and chemical or photometric measurement is acceptable, electrophoresis followed by densitometry, we found, is simply too unreliable to be used in tests that establish genetic diagnoses or are used to screen antenatal women for fetal diseases.

We, the authors, would be happy to discuss the findings and our experiences with interested readers at the email provided at the publisher website.

On 2015 Jun 30, Prashant Sharma, MD, DM commented:

This paper basically addresses a cost-cutting issue that sometimes unfortunately still surfaces in resource-poor settings, wherein electrophoresis-derived hemoglobin fraction percentages are used for clinical decision making.

While electrophoresis followed by elution and chemical or photometric measurement is acceptable, electrophoresis followed by densitometry, we found, is simply too unreliable to be used in tests that establish genetic diagnoses or are used to screen antenatal women for fetal diseases.

We, the authors, would be happy to discuss the findings and our experiences with interested readers at the email provided at the publisher website.