2 Matching Annotations
  1. Jul 2018
    1. On 2016 Jun 16, Lanfranco Troncone commented:

      Adding to the discussion on the role of monoamines in violent aggression, this new data shed light on results we published many years ago on three models of aggression in REM sleep deprived rats. Aggression can be elicited in these animals by dopaminergic agonists like apomorphine, dopamine/noradrenaline precursor L-DOPA and noradrenaline synthesis inhibition by fusaric acid. We observed the clear differences in these three models and fusaric acid induced the more violent aggression while L-DOPA the most stereotyped mild boxing type. Our discussion proposed then that noradrenergic transmission was responsible for moderating the behavior while dopamine was triggering it. We offer the full paper at: Troncone LR, & Tufik, S. - Physiology & Behavior (1991), 50, 173-178 (PMID 1946713).


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  2. Feb 2018
    1. On 2016 Jun 16, Lanfranco Troncone commented:

      Adding to the discussion on the role of monoamines in violent aggression, this new data shed light on results we published many years ago on three models of aggression in REM sleep deprived rats. Aggression can be elicited in these animals by dopaminergic agonists like apomorphine, dopamine/noradrenaline precursor L-DOPA and noradrenaline synthesis inhibition by fusaric acid. We observed the clear differences in these three models and fusaric acid induced the more violent aggression while L-DOPA the most stereotyped mild boxing type. Our discussion proposed then that noradrenergic transmission was responsible for moderating the behavior while dopamine was triggering it. We offer the full paper at: Troncone LR, & Tufik, S. - Physiology & Behavior (1991), 50, 173-178 (PMID 1946713).


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.