2 Matching Annotations
  1. Jul 2018
    1. On 2015 Nov 18, Alvaro Alonso commented:

      Just a couple of comments. 1. I am somewhat surprised that this is described as a 'case-control study' since it seems to be a cohort study with an exposed group (children from mothers who received a diagnosed of cancer during pregnancy) matched to an unexposed group (children from mothers without a cancer diagnosis), and followed up for outcomes. 2. The results show that, even if the differences were not significant, exposed children had >40% increased risk of low birth weight and higher risk of other outcomes. Based on these data, I do not think the authors have enough evidence to conclude that maternal cancer did not lead to worse outcomes in children.


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  2. Feb 2018
    1. On 2015 Nov 18, Alvaro Alonso commented:

      Just a couple of comments. 1. I am somewhat surprised that this is described as a 'case-control study' since it seems to be a cohort study with an exposed group (children from mothers who received a diagnosed of cancer during pregnancy) matched to an unexposed group (children from mothers without a cancer diagnosis), and followed up for outcomes. 2. The results show that, even if the differences were not significant, exposed children had >40% increased risk of low birth weight and higher risk of other outcomes. Based on these data, I do not think the authors have enough evidence to conclude that maternal cancer did not lead to worse outcomes in children.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.