4 Matching Annotations
  1. Jul 2018
    1. On 2015 Dec 14, Víctor Bustamante commented:

      The Figure 1 shows the effect of the presence or absence of glucose on the activity of the Csr system, and, as consequence of this, the expected effect on some phenotypes controlled by Csr. Based on these depicted findings, the presence of glucose would favor motility through the glucose-specific PTS and Csr system, which is consistent with many reports indicating that glucose is a major attractant for motility (Deepika et al., 2015; Kim et al., 2011; Kim and Kim, 2010; Lai et al., 1997). Certainly, there are some reports indicating that the presence of glucose prevents synthesis of flagella. Since the expression of flagella is a process highly regulated by multiple mechanisms acting independently in response to the presence or not of different environmental cues, discrepancies between these studies could be due to the conditions tested.


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    2. On 2015 Dec 11, Martine Crasnier-Mednansky commented:

      The contention 'motility occurs in the presence of glucose', as depicted in Figure 1, is erroneous. Presence of glucose prevents synthesis of flagella in E. coli (Adler J, 1967), and cAMP is 'absolutely' required for flagella formation (Yokota T, 1970); see also Fahrner KA, 2015.


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  2. Feb 2018
    1. On 2015 Dec 11, Martine Crasnier-Mednansky commented:

      The contention 'motility occurs in the presence of glucose', as depicted in Figure 1, is erroneous. Presence of glucose prevents synthesis of flagella in E. coli (Adler J, 1967), and cAMP is 'absolutely' required for flagella formation (Yokota T, 1970); see also Fahrner KA, 2015.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

    2. On 2015 Dec 14, Víctor Bustamante commented:

      The Figure 1 shows the effect of the presence or absence of glucose on the activity of the Csr system, and, as consequence of this, the expected effect on some phenotypes controlled by Csr. Based on these depicted findings, the presence of glucose would favor motility through the glucose-specific PTS and Csr system, which is consistent with many reports indicating that glucose is a major attractant for motility (Deepika et al., 2015; Kim et al., 2011; Kim and Kim, 2010; Lai et al., 1997). Certainly, there are some reports indicating that the presence of glucose prevents synthesis of flagella. Since the expression of flagella is a process highly regulated by multiple mechanisms acting independently in response to the presence or not of different environmental cues, discrepancies between these studies could be due to the conditions tested.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.