On 2016 Feb 27, Jim Woodgett commented:
Interested in testing this further in either conditional or global GSK-3 KOs (would also get at possible isoform issue)? We found this approach effective in comparing a different GSK-3 small molecule inhibitor with a GSK-3alpha KO in another model of schizophrenia (DISC1 L100P: http://www.ncbi.nlm.nih.gov/pubmed/20687111). Also rescued behavioural deficits.
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