2 Matching Annotations
  1. Jul 2018
    1. On 2016 May 04, Richard Unwin commented:

      Hmmm,

      Care should be taken with the interpretation of results in this study. The age matching between the case (HD) and control groups is not great.

      Cases have a mean +/- s.d. age at death of 57+/-12.3, while the controls are 79 +/- 13.45. A Welch’s T-test comparing these data gives p=0.00011. The observations made in this study could therefore simply be normal changes in the ageing brain, rather than as a result of HD?


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  2. Feb 2018
    1. On 2016 May 04, Richard Unwin commented:

      Hmmm,

      Care should be taken with the interpretation of results in this study. The age matching between the case (HD) and control groups is not great.

      Cases have a mean +/- s.d. age at death of 57+/-12.3, while the controls are 79 +/- 13.45. A Welch’s T-test comparing these data gives p=0.00011. The observations made in this study could therefore simply be normal changes in the ageing brain, rather than as a result of HD?


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.