On 2016 Nov 17, Jean-Jacques Letesson commented:

In the starting paragraph of the discussion the authors wrote "Metabolism and usage of erythritol are regulated by the 7.7‑kb ery operon, which consists of four genes eryA, eryB, eryC and eryD (EryA, 519 AA; EryB, 502 AA; EryC, 309 AA and EryD, 316 AA). The functions of these four proteases are similar to xylulose kinase (E. coli xylB), glycerol‑3‑phosphate"

I have two major comments on this sentences:

1- THESE GENES ARE NOT PROTEASES: ery is a kinase, eryB is a dehydrogenase, eryC an isomerase and eryD a transcriptional regulator

2- The EryABCD ery operon is by itself not sufficient to catabolize erythritol as published recently (Barbier T. et al., 2014.PNAS 111:17815–17820.) you need two more isomerase (eryH and eryI)

On 2016 Nov 17, Jean-Jacques Letesson commented:

In the starting paragraph of the discussion the authors wrote "Metabolism and usage of erythritol are regulated by the 7.7‑kb ery operon, which consists of four genes eryA, eryB, eryC and eryD (EryA, 519 AA; EryB, 502 AA; EryC, 309 AA and EryD, 316 AA). The functions of these four proteases are similar to xylulose kinase (E. coli xylB), glycerol‑3‑phosphate"

I have two major comments on this sentences:

1- THESE GENES ARE NOT PROTEASES: ery is a kinase, eryB is a dehydrogenase, eryC an isomerase and eryD a transcriptional regulator

2- The EryABCD ery operon is by itself not sufficient to catabolize erythritol as published recently (Barbier T. et al., 2014.PNAS 111:17815–17820.) you need two more isomerase (eryH and eryI)