On 2017 Jan 23, Scott D Slotnick commented:

There has been a call for peer commentary on the Editorial/Discussion Paper (Slotnick SD, 2017) in the journal Cognitive Neuroscience (due February 13th, 2017). The Editorial/Discussion Paper, Commentaries, and an Author Response will be published in an issue of Cognitive Neuroscience later this year.

On 2017 Jan 04, Gerard Ridgway commented:

This editorial suggests that the problems identified by Eklund A, 2016 arise solely from the use of resting-state data in place of null data. It seems to overlook the fact that Eklund A, 2016 use randomly timed designs (two blocked designs and two event-related), meaning the unknown timecourse of default mode network activity cannot consistently give rise to design-synchronised activation (except perhaps in the special case of the initial transients, which is mentioned briefly in an article by Flandin and Friston, 2016, but probably warrants further investigation). On the other hand, the activity of the DMN could perhaps be contributing to non-Gaussianity of the residuals and/or a more complex spatial autocorrelation function (ACF) than is typically modelled, but these aspects seem not to be mentioned, or to be addressed in the author's recommended simulation approach (which seems to be very similar to the original AlphaSim from AFNI).

Regarding the spatial ACF in particular, but also the issue of the cluster-defining threshold (CDT), this article should be contrasted with Cox et al., 2016, which recommends a new long-tailed non-Gaussian ACF available in newer versions of AlphaSim, together with a CDT of 0.001 or below.

On 2017 Jan 04, Gerard Ridgway commented:

This editorial suggests that the problems identified by Eklund A, 2016 arise solely from the use of resting-state data in place of null data. It seems to overlook the fact that Eklund A, 2016 use randomly timed designs (two blocked designs and two event-related), meaning the unknown timecourse of default mode network activity cannot consistently give rise to design-synchronised activation (except perhaps in the special case of the initial transients, which is mentioned briefly in an article by Flandin and Friston, 2016, but probably warrants further investigation). On the other hand, the activity of the DMN could perhaps be contributing to non-Gaussianity of the residuals and/or a more complex spatial autocorrelation function (ACF) than is typically modelled, but these aspects seem not to be mentioned, or to be addressed in the author's recommended simulation approach (which seems to be very similar to the original AlphaSim from AFNI).

Regarding the spatial ACF in particular, but also the issue of the cluster-defining threshold (CDT), this article should be contrasted with Cox et al., 2016, which recommends a new long-tailed non-Gaussian ACF available in newer versions of AlphaSim, together with a CDT of 0.001 or below.

On 2017 Jan 23, Scott D Slotnick commented:

There has been a call for peer commentary on the Editorial/Discussion Paper (Slotnick SD, 2017) in the journal Cognitive Neuroscience (due February 13th, 2017). The Editorial/Discussion Paper, Commentaries, and an Author Response will be published in an issue of Cognitive Neuroscience later this year.