- Jul 2018
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europepmc.org europepmc.org
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On 2018 Jan 08, Israel Hanukoglu commented:
A three dimensional (3D) video of the human eccrine sweat gland duct covered with sodium channels can be seen at: https://www.youtube.com/watch?v=JcddOILffOM
The video was generated based on the results of this study.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY. -
On 2017 May 17, Israel Hanukoglu commented:
Our lab has undertaken to map the sites of expression and localization of ENaC and CFTR in epithelial tissues. This article is the second one in the series and it concentrates on the skin.
In the first paper, we covered the sites of localization of ENaC and CFTR in the respiratory tract and the female reproductive tract. Both of these tissues contain large stretches of epithelium covered with multi-ciliated cells. We had shown that in these epithelia with motile cilia, ENaC is expressed along the entire length of the cilia. Reference: https://www.ncbi.nlm.nih.gov/pubmed/22207244
In the current work on the skin, epidermis and epidermal appendages, ENaC was found mostly located in the cytoplasm of keratinocytes, sebaceous glands, and smooth muscle cells. Only in the eccrine type sweat glands, ENaC and CFTR were found predominantly on the luminal membrane facing the lumen of the ducts. Thus, the reuptake of Na+ ions secreted in sweat probably takes place in the eccrine glands.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
-
europepmc.org europepmc.org
-
On 2017 May 17, Israel Hanukoglu commented:
Our lab has undertaken to map the sites of expression and localization of ENaC and CFTR in epithelial tissues. This article is the second one in the series and it concentrates on the skin.
In the first paper, we covered the sites of localization of ENaC and CFTR in the respiratory tract and the female reproductive tract. Both of these tissues contain large stretches of epithelium covered with multi-ciliated cells. We had shown that in these epithelia with motile cilia, ENaC is expressed along the entire length of the cilia. Reference: https://www.ncbi.nlm.nih.gov/pubmed/22207244
In the current work on the skin, epidermis and epidermal appendages, ENaC was found mostly located in the cytoplasm of keratinocytes, sebaceous glands, and smooth muscle cells. Only in the eccrine type sweat glands, ENaC and CFTR were found predominantly on the luminal membrane facing the lumen of the ducts. Thus, the reuptake of Na+ ions secreted in sweat probably takes place in the eccrine glands.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY. -
On 2018 Jan 08, Israel Hanukoglu commented:
A three dimensional (3D) video of the human eccrine sweat gland duct covered with sodium channels can be seen at: https://www.youtube.com/watch?v=JcddOILffOM
The video was generated based on the results of this study.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
-