On 2017 Apr 02, William McAuliffe commented:

This is a valuable addition to the literature, but its generalizability is limited by the recruitment source of the prescription group. Most iatrogenically addicted patients do not seek treatment in a drug treatment program because of the demographic differences between them and the typical non-medical opioid addict. The pain patients are much more likely go to a pain clinic or are simply tapered off of the drug by the original providers. There are important differences between the pain patients that go to drug treatment programs and those that go to pain clinics that are attenuated in this study and likely result in its failure to find many significant effects.

On 2017 Apr 02, William McAuliffe commented:

This is a valuable addition to the literature, but its generalizability is limited by the recruitment source of the prescription group. Most iatrogenically addicted patients do not seek treatment in a drug treatment program because of the demographic differences between them and the typical non-medical opioid addict. The pain patients are much more likely go to a pain clinic or are simply tapered off of the drug by the original providers. There are important differences between the pain patients that go to drug treatment programs and those that go to pain clinics that are attenuated in this study and likely result in its failure to find many significant effects.