On 2017 Jun 01, Andrea Brancaccio commented:

An interesting and solid biochemical work. As the Authors have stated “the POMTs are suggested to have exquisitely narrow glycosylation functions of α-DG”. As an additional note of some interest, it may be worth considering that POMTs predate dystroglycan. In fact, orthologous members of this family can be found in Capsaspora owczarzaki (Accession: XP004363497) or also in Monosiga brevicollis (Accession: XP001744300) belonging respectively to Filasterea and Choanoflagellata, two unicellular groups, close to early-diverging metazoans, in which dystroglycan had not been found (see Adams JC and Brancaccio A., The evolution of the dystroglycan complex, a major mediator of muscle integrity. Biol Open. 2015 4:1163-79, Adams JC, 2015).

On 2017 Jun 01, Andrea Brancaccio commented:

An interesting and solid biochemical work. As the Authors have stated “the POMTs are suggested to have exquisitely narrow glycosylation functions of α-DG”. As an additional note of some interest, it may be worth considering that POMTs predate dystroglycan. In fact, orthologous members of this family can be found in Capsaspora owczarzaki (Accession: XP004363497) or also in Monosiga brevicollis (Accession: XP001744300) belonging respectively to Filasterea and Choanoflagellata, two unicellular groups, close to early-diverging metazoans, in which dystroglycan had not been found (see Adams JC and Brancaccio A., The evolution of the dystroglycan complex, a major mediator of muscle integrity. Biol Open. 2015 4:1163-79, Adams JC, 2015).