On 2017 Dec 15, Ricky Turgeon commented:

Duplication of PLATO data in meta-analyses

Upon reviewing this meta-analysis, I noticed that the data from PLATO have inadvertently been duplicated in all meta-analyses of clinical outcomes in this review. This was done by including both the results of the primary publication (Wallentin et al, NEJM 2009 - reference 28 in this article) and the subgroup of PLATO patients planned for an invasive strategy (Cannon et al, Lancet 2010 - reference 21).

Ideally, this review should be retracted and republished in its corrected form that excludes the double-counting of events and ~13,000 participants from the Cannon, et al Lancet 2010 subgroup analysis of PLATO.

Sincerely, Ricky Turgeon BSc(Pharm), ACPR, PharmD

(copy of comment posted on PLOS ONE)

On 2017 Dec 15, Ricky Turgeon commented:

Duplication of PLATO data in meta-analyses

Upon reviewing this meta-analysis, I noticed that the data from PLATO have inadvertently been duplicated in all meta-analyses of clinical outcomes in this review. This was done by including both the results of the primary publication (Wallentin et al, NEJM 2009 - reference 28 in this article) and the subgroup of PLATO patients planned for an invasive strategy (Cannon et al, Lancet 2010 - reference 21).

Ideally, this review should be retracted and republished in its corrected form that excludes the double-counting of events and ~13,000 participants from the Cannon, et al Lancet 2010 subgroup analysis of PLATO.

Sincerely, Ricky Turgeon BSc(Pharm), ACPR, PharmD

(copy of comment posted on PLOS ONE)