On 2017 Sep 21, Daniel Corcos commented:

The reason why the reduction in breast cancer mortality is overestimated is because the reason for the lack of efficiency of mammography screening in terms of mortality reduction has not been understood. As cancers are detected by mammography more than one year before physical examination, this must translate in a strong decrease in mortality. The fact that this strong decrease is not observed is due to the fact that mammography leads to a strong increase in cancer incidence (mistakenly considered as overdiagnosis). The barrier I see relates to information about the actual risks of low-dose irradiation.

On 2017 Sep 21, Daniel Corcos commented:

The reason why the reduction in breast cancer mortality is overestimated is because the reason for the lack of efficiency of mammography screening in terms of mortality reduction has not been understood. As cancers are detected by mammography more than one year before physical examination, this must translate in a strong decrease in mortality. The fact that this strong decrease is not observed is due to the fact that mammography leads to a strong increase in cancer incidence (mistakenly considered as overdiagnosis). The barrier I see relates to information about the actual risks of low-dose irradiation.