2 Matching Annotations
  1. Jul 2018
    1. On 2014 Jan 11, Brett Snodgrass commented:

      Dear Reader,

      Please provide your kind consideration to the following reasons that some of the described "lymphatic structures" may be "myocardial sinusoids."

      Quoted from the article: “The subepicardial and subendocardial systems in dogs and pigs communicate via transmyocardial channels” … "in humans these communications have not been identified with certainty." The subendocardial network of lymphatics described in both animals and humans in this study have many similarities to the myocardial sinusoids described by Wearn.

      http://bit.ly/JTWearn

      Tracing to subepicardial lymphatics was possible in dogs/pigs, but not in humans. This may be explained by the hypothesis that some of the observed “lymphatics” in both animals and humans were “myocardial sinusoids.” Caution should be exercised before assuming that all the irregular subendocardial channels reported in this study were lymphatics. Presumably, many of them were myocardial sinusoids and not lymphatics.

      Whether these myocardial sinusoids communicate with subendocardial lymphatics may be a reasonable area for further study.

      My opinion is that accurate anatomic terminology is a basic principle underlying good medical science, and I ask others to consider whether the aforementioned definitions are appropriate. If this comment is not helpful, please let me know how it might be improved. Comments and suggestions are welcome.

      Thank you very much.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.

  2. Feb 2018
    1. On 2014 Jan 11, Brett Snodgrass commented:

      Dear Reader,

      Please provide your kind consideration to the following reasons that some of the described "lymphatic structures" may be "myocardial sinusoids."

      Quoted from the article: “The subepicardial and subendocardial systems in dogs and pigs communicate via transmyocardial channels” … "in humans these communications have not been identified with certainty." The subendocardial network of lymphatics described in both animals and humans in this study have many similarities to the myocardial sinusoids described by Wearn.

      http://bit.ly/JTWearn

      Tracing to subepicardial lymphatics was possible in dogs/pigs, but not in humans. This may be explained by the hypothesis that some of the observed “lymphatics” in both animals and humans were “myocardial sinusoids.” Caution should be exercised before assuming that all the irregular subendocardial channels reported in this study were lymphatics. Presumably, many of them were myocardial sinusoids and not lymphatics.

      Whether these myocardial sinusoids communicate with subendocardial lymphatics may be a reasonable area for further study.

      My opinion is that accurate anatomic terminology is a basic principle underlying good medical science, and I ask others to consider whether the aforementioned definitions are appropriate. If this comment is not helpful, please let me know how it might be improved. Comments and suggestions are welcome.

      Thank you very much.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.