On 2015 Jun 15, Salzman Lab Journal Club commented:

This of course is a landmark paper, clearly and concisely demonstrating that RNA alone can catalyze reactions. A finding that is a bit obscure here is that nicked circle IVS has mobility similar to linear IVS minus 15 nt. A later paper by the Cech group showed that this is because the autocyclization reaction cleaves off the 5'-most 15 nt of the linear IVS; they posit that this may limit the reversibility of the splicing reaction. This paper introduced the term "ribozyme", which the authors used in distinction to "enzyme" since the RNA reaction was not multiple-turnover; however these days it has expanded to include any RNA catalysts.

On 2015 Jun 15, Salzman Lab Journal Club commented:

This of course is a landmark paper, clearly and concisely demonstrating that RNA alone can catalyze reactions. A finding that is a bit obscure here is that nicked circle IVS has mobility similar to linear IVS minus 15 nt. A later paper by the Cech group showed that this is because the autocyclization reaction cleaves off the 5'-most 15 nt of the linear IVS; they posit that this may limit the reversibility of the splicing reaction. This paper introduced the term "ribozyme", which the authors used in distinction to "enzyme" since the RNA reaction was not multiple-turnover; however these days it has expanded to include any RNA catalysts.