138 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12905373/
  3. Jan 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic and Pancreatic Cellular Response to Early Life Nutritional Mismatch
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11815087/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12807472/
  6. Dec 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of Sec61α2 Translocon in Insulin Biosynthesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11579409/
  8. Nov 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LY6H is a marker of human pancreatic delta cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12474887/
  10. Aug 2025
  11. www.sciencedirect.com www.sciencedirect.com
    A vascular-associated fibroblastic cell controls pancreatic islet immunity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472500960X
  12. www.cell.com www.cell.com
    HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-metabolism/abstract/S1550-4131(25)00334-1
  13. Jul 2025
  14. www.sciencedirect.com www.sciencedirect.com
    Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725008368
  15. Jun 2025
  16. www.sciencedirect.com www.sciencedirect.com
    ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590925002243
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12152102/
  18. May 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S153458072500262X
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ductal or Ngn3+ cells do not contribute to adult pancreatic islet beta-cell neogenesis in homeostasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12084597/
  21. Apr 2025
  22. www.embopress.org www.embopress.org
    Ductal or Ngn3+ cells do not contribute to adult pancreatic islet beta-cell neogenesis in homeostasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    embopress.org/doi/10.1038/s44318-025-00434-z
  23. Mar 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Pancreatic alpha and beta cell fate choice is directed by apical-basal polarity dynamics
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580725001133
  25. Dec 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724013457
  27. Sep 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S155041311830576X
  29. www.sciencedirect.com www.sciencedirect.com
    Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590924002935
  30. Aug 2024
  31. academic.oup.com academic.oup.com
    Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/6/1701/3063793/Incretin-Therapies-Do-Not-Expand-Cell-Mass-or
  32. www.cell.com www.cell.com
    Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-metabolism/abstract/S1550-4131(17)30294-2
  33. Jul 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Implications of noncoding regulatory functions in the development of insulinomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666979X24001988
  35. Jun 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D Model of Mouse Embryonic Pancreas and Endocrine Compartment using Stem Cell-Derived Mesoderm and Pancreatic Progenitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11144751/
  37. Apr 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11033163/
  39. www.sciencedirect.com www.sciencedirect.com
    Developmental programming: Testosterone excess masculinizes female pancreatic transcriptome and function in sheep
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S030372072400090X
  40. Mar 2024
  41. www.sciencedirect.com www.sciencedirect.com
    OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724003206
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10955614/
  43. Feb 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of Metabolic Alterations in the Lean Metabolically Unhealthy Alpha Defensin Transgenic mice.
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10839648/
  45. Jan 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724000317
  47. www.sciencedirect.com www.sciencedirect.com
    TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724000019
  48. Dec 2023
  49. 52.53.155.43 52.53.155.43
    bqad181-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/cfe9891d0d0ceeaebc125af1d3c4163a40f55fd9/bqad181-html.html
  50. Nov 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413123003698
  52. Sep 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
  54. Aug 2023
  55. 52.53.155.43 52.53.155.43
    mmc2-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/1d6fcb3da8d247db7f5f06335281931ae65a615c/mmc2-html.html
  56. link.springer.com link.springer.com
    SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00125-023-05979-4
  57. Jul 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223013883
  59. Jun 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Nutrient-dependent regulation of β-cell proinsulin content
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0021925823018641
  61. May 2023
  62. academic.oup.com academic.oup.com
    Biosynthetic activity differs between islet cell types and in beta cells is modulated by glucose and not by secretion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/162/3/bqaa239/6047597
  63. Apr 2023
  64. www.sciencedirect.com www.sciencedirect.com
    Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580723001077
  65. www.sciencedirect.com www.sciencedirect.com
    Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590923000747
  66. Feb 2023
  67. www.sciencedirect.com www.sciencedirect.com
    Chronic cortisol elevation restricts glucose uptake but not insulin responsiveness in zebrafish skeletal muscle
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0016648023000369
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAMSAP2 localizes to the Golgi in islet β-cells and facilitates Golgi-ER trafficking
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9883185/
  69. Jan 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379122004438
  71. Nov 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472201484X
  73. Oct 2022
  74. academic.oup.com academic.oup.com
    The mineralocorticoid receptor functions as a key glucose regulator in the skeletal muscle of zebrafish
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/163/11/bqac149/6679268
  75. Aug 2022
  76. www.sciencedirect.com www.sciencedirect.com
    Differentiation of beta-like cells from human induced pluripotent stem cell-derived pancreatic progenitor organoids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166722005366
  77. www.sciencedirect.com www.sciencedirect.com
    Macrophages and neutrophils are necessary for ER stress-induced β cell loss
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722010737
  78. www.sciencedirect.com www.sciencedirect.com
    Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580722005317
  79. academic.oup.com academic.oup.com
    Circulating 1,5-anhydroglucitol as a biomarker of ß-cell mass independent of a diabetes phenotype in human subjects
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac444/6648530
  80. www.sciencedirect.com www.sciencedirect.com
    The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722009834
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optical Clearing and 3D Analysis Optimized for Mouse and Human Pancreata
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8376577/
  82. Jul 2022
  83. www.sciencedirect.com www.sciencedirect.com
    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722009263
  84. Apr 2022
  85. academic.oup.com academic.oup.com
    G209R mutant mouse as a model for human PCSK1 polyendocrinopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article-abstract/163/5/bqac024/6542675
  86. Mar 2022
  87. www.sciencedirect.com www.sciencedirect.com
    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722001498
  88. Feb 2022
  89. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubmed.ncbi.nlm.nih.gov/35172145/
  90. link.springer.com link.springer.com
    CDNF and MANF regulate ER stress in a tissue-specific manner
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00018-022-04157-w
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7611554/
  92. www.sciencedirect.com www.sciencedirect.com
    A distinct hypothalamus-to-β cell circuit modulates insulin secretion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413121006574
  93. Jan 2022
  94. diabetesjournals.org diabetesjournals.org
    Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    diabetesjournals.org/diabetes/article/70/12/2837/139076/Syntaxin-4-Enrichment-in-Cells-Prevents-Conversion
  95. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artemether and aspterric acid induce pancreatic α cells to transdifferentiate into β cells in zebrafish
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15769
  96. Dec 2021
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isoform-specific roles of prolyl hydroxylases in the regulation of pancreatic β-cell function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8643417/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis of the pancreas and islets reveals unexpected findings in human male with type 1 diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8633619/
  99. Nov 2021
  100. www.sciencedirect.com www.sciencedirect.com
    IL-1beta promotes the age-associated decline of beta cell function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004221012190
  101. Sep 2021
  102. link.springer.com link.springer.com
    Immunoregulated insulitis and slow-progressing type 1 diabetes after duodenopancreatectomy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00125-021-05563-8
  103. www.sciencedirect.com www.sciencedirect.com
    The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580721006730
  104. Aug 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6287593/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6200393/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5501713/
  108. academic.oup.com academic.oup.com
    Age-dependent changes in glucose homeostasis in male deiodinase type 2 knockout zebrafish
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/11/2759/5560170
  109. elifesciences.org elifesciences.org
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/39689
  110. academic.oup.com academic.oup.com
    The loss of ARNT/HIF1β in male pancreatic β-cells is protective against high fat diet-induced diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/12/2825/5580049
  111. Jul 2021
  112. www.nature.com www.nature.com
    Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-021-24788-0
  113. academic.oup.com academic.oup.com
    Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/5/979/5371334
  114. www.sciencedirect.com www.sciencedirect.com
    Local Integrin Activation in Pancreatic β Cells Targets Insulin Secretion to the Vasculature
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718313068
  115. academic.oup.com academic.oup.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/159/9/3245/5055753
  116. academic.oup.com academic.oup.com
    The loss of ARNT/HIF1β in male pancreatic β-cells is protective against high fat diet-induced diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/12/2825/5580049
  117. www.sciencedirect.com www.sciencedirect.com
    Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0960982219307596
  118. www.sciencedirect.com www.sciencedirect.com
    Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413118307423
  119. Jun 2021
  120. www.sciencedirect.com www.sciencedirect.com
    Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945621002567
  121. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infection induces beta cell transdifferentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413121002321
  122. May 2021
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adiponectin preserves metabolic fitness during aging
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8099426/
  124. Apr 2021
  125. www.sciencedirect.com www.sciencedirect.com
    In vitro assembly of peri-islet basement membrane-like structures
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0142961221001642
  126. Feb 2021
  127. academic.oup.com academic.oup.com
    Ins1-Cre and Ins1-Cre ER gene replacement alleles are susceptible to silencing by DNA hypermethylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/161/8/bqaa054/5817889
  128. academic.oup.com academic.oup.com
    MiR-221/222 inhibit insulin production of pancreatic β-cells in mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/161/1/bqz027/5639771
  129. Jan 2021
  130. www.sciencedirect.com www.sciencedirect.com
    Protocol for determining zinc-dependent β cell-selective small-molecule delivery in mouse pancreas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166720302501
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
  132. Sep 2020
  133. academic.oup.com academic.oup.com
    Dapagliflozin does not directly affect human α or β cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/161/8/bqaa080/5840747
  134. www.sciencedirect.com www.sciencedirect.com
    The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720300917
  135. elifesciences.org elifesciences.org
    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/58659
  136. www.sciencedirect.com www.sciencedirect.com
    Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720303478
  137. academic.oup.com academic.oup.com
    Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/6/1701/3063793/Incretin-Therapies-Do-Not-Expand-Cell-Mass-or
  138. www.sciencedirect.com www.sciencedirect.com
    Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720306306
  139. www.sciencedirect.com www.sciencedirect.com
    Protocol for Studying Reprogramming of Mouse Pancreatic Acinar Cells to β-like Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166720300836
  140. www.sciencedirect.com www.sciencedirect.com
    REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720305404
  141. www.sciencedirect.com www.sciencedirect.com
    Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720307415
  142. www.sciencedirect.com www.sciencedirect.com
    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580720300162
  143. www.sciencedirect.com www.sciencedirect.com
    ZIGIR, a Granule-Specific Zn2+ Indicator, Reveals Human Islet α Cell Heterogeneity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720308858
  144. www.sciencedirect.com www.sciencedirect.com
    A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590920302824
  145. www.sciencedirect.com www.sciencedirect.com
    Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580720302707
  146. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Microsoft Word - DB190554SupplementaryData.doc
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    diabetes.diabetesjournals.org/content/diabetes/suppl/2019/10/09/db19-0554.DC1/DB190554SupplementaryData.pdf
  147. journals.physiology.org journals.physiology.org
    Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner | American Journal of Physiology-Endocrinology and Metabolism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    journals.physiology.org/doi/full/10.1152/ajpendo.00473.2019
  148. May 2020
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes
    1
    1. nPOD_Curator 15 May 2020
      Immunohistochemistry was performed using a standard immunoperoxidase approach, as previously described [21]. To examine multiple antigens within the same FFPE section, samples were probed in a sequential manner with up to three different antibodies (ESM Tables 3, 4). The mean fluorescence intensity (MFI) of stained antigens was measured using ImageJ Version 1.50b Java 1.8.0_77; https://imagej.nih.gov/ij/download.html. Some slides were processed with isotype control antisera to confirm the specificity of labelling (ESM Fig. 1). Frozen sections were stained using a standard immunofluorescence approach [22].

      Immunohistochemistry

      (HLA, Ins, Glu, NLRC5, STAT1, B2M abs determined from supplementary)

      obiwan:Method PMID:27506584 RRID:AB_1269092 RRID:AB_10013624 RRID:AB_1658481 RRID:AB_11129988 RRID:AB_303057 RRID:AB_10933380 RRID:AB_2716551
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5042874/
  150. Jan 2020
  151. www.sciencedirect.com www.sciencedirect.com
    A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580719303892
  152. www.jbc.org www.jbc.org
    The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jbc.org/content/294/13/4889.full
  153. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413119306709
  154. link.springer.com link.springer.com
    Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00125-019-05030-5
  155. academic.oup.com academic.oup.com
    Teriparatide Improves Bone and Lipid Metabolism in a Male Rat Model of Type 2 Diabetes Mellitus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/10/2339/5536623
  156. www.sciencedirect.com www.sciencedirect.com
    Pancreatic endocrine cell arrangement during human ontogeny
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0065128118303416
  157. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945618303799
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6294552/
  159. www.sciencedirect.com www.sciencedirect.com
    Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S155041311930021X
  160. academic.oup.com academic.oup.com
    Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/160/5/979/5371334
  161. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580718309195
  162. Nov 2018
  163. academic.oup.com academic.oup.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/159/11/3674/5094960
  164. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S155041311830576X
  165. link.springer.com link.springer.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00441-018-2921-z
  166. academic.oup.com academic.oup.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/159/9/3143/4917526
  167. www.sciencedirect.com www.sciencedirect.com
    GABA and Artesunate Do Not Induce Pancreatic α-to-β Cell Transdifferentiation In Vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413118304455
  168. www.sciencedirect.com www.sciencedirect.com
    Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413118300676
  169. www.sciencedirect.com www.sciencedirect.com
    Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580718304179
  170. www.sciencedirect.com www.sciencedirect.com
    Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1074761317304703
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hospital time prior to death and pancreas histopathology: implications for future studies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5844815/
  172. Nov 2017
  173. www.sciencedirect.com www.sciencedirect.com
    Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S155041311730219X
  174. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413117302991
  175. www.sciencedirect.com www.sciencedirect.com
    Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413117303005
  176. www.sciencedirect.com www.sciencedirect.com
    Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413117302942
  177. www.sciencedirect.com www.sciencedirect.com
    N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413117302176
  178. academic.oup.com academic.oup.com
    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/6/1659/3058741/Guanabenz-Sensitizes-Pancreatic-Cells-to-Lipotoxic
  179. academic.oup.com academic.oup.com
    Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/6/1701/3063793/Incretin-Therapies-Do-Not-Expand-Cell-Mass-or
  180. academic.oup.com academic.oup.com
    RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep Islets
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/158/4/743/2991881/RNA-Sequencing-Exposes-Adaptive-and-Immune
  181. academic.oup.com academic.oup.com
    Maternal Low Protein Isocaloric Diet Suppresses Pancreatic β-Cell Proliferation in Mouse Offspring via miR-15b
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/endo/article/157/12/4782/2758433/Maternal-Low-Protein-Isocaloric-Diet-Suppresses
  182. www.sciencedirect.com www.sciencedirect.com
    Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413117301699
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5224921/
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5154760/
  185. www.sciencedirect.com www.sciencedirect.com
    Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867416315239
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An alternative splicing program promotes adipose tissue thermogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5026472/