24 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual molecular therapy targeting tumor cell heterogeneity improves therapeutic efficacy in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12496224/
  3. Aug 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis
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    sciencedirect.com/science/article/pii/S2211124725009453
  5. Jun 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Impact of the tumor immune contexture in microsatellite-stable metastatic colorectal cancer treated with avelumab, cetuximab, and irinotecan
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    sciencedirect.com/science/article/pii/S2666379125002745
  7. Apr 2025
  8. www.sciencedirect.com www.sciencedirect.com
    Epigenomic regulation of stemness contributes to the low immunogenicity of the most mutated human cancer
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    sciencedirect.com/science/article/pii/S2211124725003328
  9. Oct 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence of human pancreatic beta cells enhances functional maturation through chromatin reorganization and promotes interferon responsiveness
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    ncbi.nlm.nih.gov/pmc/articles/PMC11194086/
  13. Apr 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    sciencedirect.com/science/article/pii/S1535610824000916
  15. Mar 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897543/
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    sciencedirect.com/science/article/pii/S2589004224000221
  19. Aug 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10401426/
  21. May 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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    sciencedirect.com/science/article/pii/S1550413123001407
  23. Sep 2022
  24. www.sciencedirect.com www.sciencedirect.com
    A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy
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    sciencedirect.com/science/article/pii/S153561082200318X
  25. Aug 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Cancer genes disfavoring T cell immunity identified via integrated systems approach
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    sciencedirect.com/science/article/pii/S2211124722009627
  27. Mar 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
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    sciencedirect.com/science/article/pii/S0092867422001428
  29. Oct 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis
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    sciencedirect.com/science/article/pii/S2666379121002810
  31. Aug 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5487217/
  33. Jul 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance
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    sciencedirect.com/science/article/pii/S1097276518310967
  35. May 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
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    sciencedirect.com/science/article/pii/S1074761320304672
  37. Sep 2020
  38. www.sciencedirect.com www.sciencedirect.com
    Virus-Mediated Suppression of the Antigen Presentation Molecule MR1
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    sciencedirect.com/science/article/pii/S2211124720301716
  39. May 2020
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes
    1
    1. nPOD_Curator 15 May 2020
      Immunohistochemistry was performed using a standard immunoperoxidase approach, as previously described [21]. To examine multiple antigens within the same FFPE section, samples were probed in a sequential manner with up to three different antibodies (ESM Tables 3, 4). The mean fluorescence intensity (MFI) of stained antigens was measured using ImageJ Version 1.50b Java 1.8.0_77; https://imagej.nih.gov/ij/download.html. Some slides were processed with isotype control antisera to confirm the specificity of labelling (ESM Fig. 1). Frozen sections were stained using a standard immunofluorescence approach [22].

      Immunohistochemistry

      (HLA, Ins, Glu, NLRC5, STAT1, B2M abs determined from supplementary)

      obiwan:Method PMID:27506584 RRID:AB_1269092 RRID:AB_10013624 RRID:AB_1658481 RRID:AB_11129988 RRID:AB_303057 RRID:AB_10933380 RRID:AB_2716551
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    ncbi.nlm.nih.gov/pmc/articles/PMC5042874/
  41. Jan 2020
  42. academic.oup.com academic.oup.com
    Pathogenesis of anti-PIT-1 antibody syndrome: PIT-1 presentation by HLA class I on anterior pituitary cells
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    academic.oup.com/jes/article/3/11/1969/5554101
  43. Nov 2018
  44. www.sciencedirect.com www.sciencedirect.com
    A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
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    sciencedirect.com/science/article/pii/S1535610818301259
  45. Nov 2017
  46. elifesciences.org elifesciences.org
    Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
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    elifesciences.org/articles/25306
  47. www.sciencedirect.com www.sciencedirect.com
    Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses
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    sciencedirect.com/science/article/pii/S0092867417304270