94 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    1. scibot 20 Nov 2024
      RRID:AB_11042766

      DOI: 10.1016/j.molcel.2024.10.025

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    sciencedirect.com/science/article/pii/S1097276524008657
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability
    1
    1. scibot 14 Nov 2024
      RRID:AB_11042766

      DOI: 10.7554/eLife.94657

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    pmc.ncbi.nlm.nih.gov/articles/PMC11554307/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
    1
    1. scibot 07 Nov 2024
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      DOI: 10.3390/cells13191654

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    pmc.ncbi.nlm.nih.gov/articles/PMC11475318/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Grb7 Ablation in Mice Improved Glycemic Control, Enhanced Insulin Signaling, and Increased Abdominal fat Mass in Females
    1
    1. scibot 07 Nov 2024
      AB_11042766

      DOI: 10.1210/endocr/bqae045

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    pmc.ncbi.nlm.nih.gov/articles/PMC11491842/
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval
    1
    1. scibot 25 Sep 2024
      RRID:AB_2687491

      DOI: 10.1016/j.celrep.2020.108312

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    sciencedirect.com/science/article/pii/S2211124720313012
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    Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis
    1
    1. scibot 25 Sep 2024
      RRID:AB_477593

      DOI: 10.1016/j.celrep.2019.10.127

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    sciencedirect.com/science/article/pii/S2211124719314603
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
    1
    1. scibot 13 Sep 2024
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      DOI: 10.3390/ijms25168595

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    ncbi.nlm.nih.gov/pmc/articles/PMC11354993/
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality
    1
    1. scibot 22 Aug 2024
      RRID:AB_11042766

      DOI: 10.7554/eLife.92826

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    ncbi.nlm.nih.gov/pmc/articles/PMC11329274/
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    Acetate enables metabolic fitness and cognitive performance during sleep disruption
    1
    1. scibot 22 Aug 2024
      AB_11042766

      DOI: 10.1016/j.cmet.2024.07.019

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    sciencedirect.com/science/article/pii/S1550413124002900
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    Antisense oligonucleotides enhance SLC20A2 expression and suppress brain calcification in a humanized mouse model
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.neuron.2024.07.013

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    sciencedirect.com/science/article/pii/S089662732400535X
  15. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
    1
    1. scibot 02 Aug 2024
      66031

      DOI: 10.1186/s13046-021-02166-4

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    jeccr.biomedcentral.com/articles/10.1186/s13046-021-02166-4
  16. Jul 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Assembly mechanism of Integrator’s RNA cleavage module
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.molcel.2024.06.032

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    sciencedirect.com/science/article/pii/S1097276524005392
  18. 52.53.155.43 52.53.155.43
    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1053/j.gastro.2024.07.016

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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1038/s41422-024-00985-6

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    pmc.ncbi.nlm.nih.gov/articles/PMC11442470/
  20. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017310-main-html.html
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.isci.2024.110506

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    A cingulate-hippocampal circuit mediates early depressive-like behavior in the mouse model of Alzheimer’s disease
    1
    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.isci.2024.109778

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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
    1
    1. scibot 03 Jul 2024
      RRID:AB_28834830

      DOI: 10.3389/fonc.2024.1394653

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    ncbi.nlm.nih.gov/pmc/articles/PMC11199525/
  23. Jun 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAc Modification Is a Promising Therapeutic Target for Diabetic Retinopathy
    1
    1. scibot 22 Jun 2024
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      DOI: 10.3390/ijms25116286

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    ncbi.nlm.nih.gov/pmc/articles/PMC11173153/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF2BP2-Shox2 axis regulates hippocampal-neuronal senescence to alleviate microgravity-induced recognition disturbance
    1
    1. scibot 08 Jun 2024
      RRID:AB_11042766

      DOI: 10.1016/j.isci.2024.109917

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    ncbi.nlm.nih.gov/pmc/articles/PMC11134919/
  26. May 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release
    1
    1. scibot 19 May 2024
      RRID:AB_11042766

      DOI: 10.1126/sciadv.adi7024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100570/
  28. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
    1
    1. scibot 17 May 2024
      RRID:AB_11042766

      DOI: 10.1016/j.molcel.2024.04.009

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    sciencedirect.com/science/article/pii/S1097276524003241
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo
    1
    1. scibot 11 May 2024
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      DOI: 10.1371/journal.pone.0302856

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    ncbi.nlm.nih.gov/pmc/articles/PMC11081324/
  30. www.sciencedirect.com www.sciencedirect.com
    An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.molcel.2024.04.010

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    sciencedirect.com/science/article/pii/S1097276524003253
  31. Apr 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy
    1
    1. scibot 11 Apr 2024
      RRID:AB_11042766

      DOI: 10.1016/j.isci.2024.109580

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    sciencedirect.com/science/article/pii/S2589004224008022
  33. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109510

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    52.53.155.43/e4a741173d4beb6859350a39a8e5091b3ba2fb02/1-s2.0-S2589004224007314-main-html.html
  34. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.ccell.2024.03.006

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    sciencedirect.com/science/article/pii/S1535610824000916
  35. Feb 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.canlet.2024.216696

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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxin-mediated silk gland organ dysfunction diverts resources to enhance silkworm fecundity by potentiating nutrient-sensing IIS/TOR pathways
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    1. scibot 03 Feb 2024
      RRID:AB_11042766

      DOI: 10.1016/j.isci.2024.108853

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830876/
  38. Jan 2024
  39. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113426

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    cell.com/cell-reports/abstract/S2211-1247(23)01438-9
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
    1
    1. scibot 05 Jan 2024
      RRID:AB_11042766

      DOI: 10.1083/jcb.202211025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10316704/
  41. Dec 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells
    1
    1. scibot 23 Dec 2023
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      DOI: 10.1016/j.isci.2023.108645

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    sciencedirect.com/science/article/pii/S2589004223027220
  43. www.sciencedirect.com www.sciencedirect.com
    Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation
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    1. scibot 20 Dec 2023
      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2023.113522

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    sciencedirect.com/science/article/pii/S2211124723015346
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    1. scibot 20 Dec 2023
      RRID:AB_11042766

      DOI: 10.1158/0008-5472.CAN-23-1065

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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
  45. 52.53.155.43 52.53.155.43
    can-23-1065-html.html
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    1. scibot 01 Dec 2023
      RRID:AB_11042766

      DOI: 10.1158/0008-5472.can-23-1065

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      RRID:AB_11042766

      DOI: 10.1158/0008-5472.can-23-1065

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    52.53.155.43/9a4ebc518d925889ddaa33b397b4737aebb3357f/can-23-1065-html.html
  46. Oct 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
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    1. scibot 20 Oct 2023
      RRID:AB_11042766

      DOI: 10.1016/j.isci.2023.108091

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    ncbi.nlm.nih.gov/pmc/articles/PMC10583057/
  48. Sep 2023
  49. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    1. scibot 22 Sep 2023
      RRID:AB_11042766

      DOI: 10.1038/s41422-023-00874-4

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    nature.com/articles/s41422-023-00874-4
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
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    1. scibot 07 Sep 2023
      RRID:AB_11042766

      DOI: 10.1016/j.isci.2023.107505

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    ncbi.nlm.nih.gov/pmc/articles/PMC10470315/
  51. Aug 2023
  52. 52.53.155.43 52.53.155.43
    PIIS221112472300952X-html.html
    1
    1. scibot 18 Aug 2023
      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2023.112941

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  53. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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  54. Jul 2023
  55. www.sciencedirect.com www.sciencedirect.com
    The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury
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    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
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    Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice
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  59. www.embopress.org www.embopress.org
    Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics
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  60. Jun 2023
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    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
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    IL-17C neutralization protects the kidney against acute injury and chronic injury
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  63. May 2023
  64. 52.53.155.43 52.53.155.43
    mcr-22-1012-html.html
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  65. www.nature.com www.nature.com
    Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus
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  66. Apr 2023
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    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
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    RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits
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    The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
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  70. Mar 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
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  72. Jan 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion
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  74. Dec 2022
  75. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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  76. Nov 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease
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  78. Oct 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia
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  80. Sep 2022
  81. www.sciencedirect.com www.sciencedirect.com
    Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity
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  82. Aug 2022
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    Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis
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  84. May 2022
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    Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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    Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function
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  88. Apr 2022
  89. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    Recycling of autophagosomal components from autolysosomes by the recycler complex
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  92. Mar 2022
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    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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  95. Oct 2021
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium
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  97. Aug 2021
  98. www.sciencedirect.com www.sciencedirect.com
    Methylation of dual-specificity phosphatase 4 controls cell differentiation
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  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low‐dose cisplatin exposure
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  100. Jul 2021
  101. www.sciencedirect.com www.sciencedirect.com
    Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense
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  104. Jun 2021
  105. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
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  106. May 2021
  107. journals.biologists.com journals.biologists.com
    Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor
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    Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis
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      DOI: 10.1016/j.immuni.2020.06.004

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  109. Apr 2021
  110. www.cell.com www.cell.com
    Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
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      RRID:AB_11042766

      DOI: 10.1016/j.cmet.2021.04.001

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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00167-4
  111. Dec 2020
  112. www.sciencedirect.com www.sciencedirect.com
    CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
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    1. scibot 07 Dec 2020
      RRID:AB_11042766

      DOI: 10.1016/j.phrs.2020.105333

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    sciencedirect.com/science/article/pii/S1043661820316418
  113. Sep 2020
  114. www.sciencedirect.com www.sciencedirect.com
    Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
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    1. scibot 13 Sep 2020
      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2020.02.090

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    sciencedirect.com/science/article/pii/S2211124720302643
  115. www.sciencedirect.com www.sciencedirect.com
    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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    1. scibot 10 Sep 2020
      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2019.12.056

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  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐127‐5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency
    1
    1. scibot 09 Sep 2020
      RRID:AB_11042766

      DOI: 10.1002/jcp.29725

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  117. www.sciencedirect.com www.sciencedirect.com
    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
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    1. scibot 07 Sep 2020
      RRID:AB_11042766

      DOI: 10.1016/j.molcel.2020.06.017

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  118. Jan 2020
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic HKDC1 Expression Contributes to Liver Metabolism
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    1. scibot 13 Jan 2020
      RRID:AB_11042766

      DOI: 10.1210/en.2018-00887

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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_11042766

      DOI: 10.7554/eLife.50850

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  121. academic.oup.com academic.oup.com
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      RRID:AB_11042766

      DOI: 10.1210/en.2018-00887

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    academic.oup.com/endo/article/160/2/313/5224519
  122. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.devcel.2018.12.017

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    sciencedirect.com/science/article/pii/S1534580718310852
  123. Nov 2018
  124. www.sciencedirect.com www.sciencedirect.com
    BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation
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    1. scibot 05 Nov 2018
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  125. www.sciencedirect.com www.sciencedirect.com
    Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
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    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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  126. www.sciencedirect.com www.sciencedirect.com
    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    sciencedirect.com/science/article/pii/S1550413118301323
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5807059/
  128. europepmc.org europepmc.org
    Untitled document
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    europepmc.org/articles/PMC5739542/
  129. Nov 2017
  130. academic.oup.com academic.oup.com
    IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells
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    1. scibot 08 Nov 2017
      AB_11042766

      Curator: @patriciaelyse_

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    academic.oup.com/endo/article/158/10/3281/3885816/IL-1-Upregulates-StAR-and-Progesterone-Production