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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
    1
    1. scibot 03 Jul 2024
      RRID:AB_28834830

      DOI: 10.3389/fonc.2024.1394653

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    ncbi.nlm.nih.gov/pmc/articles/PMC11199525/
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAc Modification Is a Promising Therapeutic Target for Diabetic Retinopathy
    1
    1. scibot 22 Jun 2024
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      DOI: 10.3390/ijms25116286

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    ncbi.nlm.nih.gov/pmc/articles/PMC11173153/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF2BP2-Shox2 axis regulates hippocampal-neuronal senescence to alleviate microgravity-induced recognition disturbance
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109917

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    ncbi.nlm.nih.gov/pmc/articles/PMC11134919/
  6. May 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release
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    1. scibot 19 May 2024
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      DOI: 10.1126/sciadv.adi7024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100570/
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    1. scibot 17 May 2024
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      DOI: 10.1016/j.molcel.2024.04.009

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    sciencedirect.com/science/article/pii/S1097276524003241
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    Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo
    1
    1. scibot 11 May 2024
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      DOI: 10.1371/journal.pone.0302856

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    ncbi.nlm.nih.gov/pmc/articles/PMC11081324/
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    An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S1097276524003253
  11. Apr 2024
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    Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109580

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    sciencedirect.com/science/article/pii/S2589004224008022
  13. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109510

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    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
    1
    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1535610824000916
  15. Feb 2024
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    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.canlet.2024.216696

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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxin-mediated silk gland organ dysfunction diverts resources to enhance silkworm fecundity by potentiating nutrient-sensing IIS/TOR pathways
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    1. scibot 03 Feb 2024
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      DOI: 10.1016/j.isci.2024.108853

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  18. Jan 2024
  19. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113426

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    cell.com/cell-reports/abstract/S2211-1247(23)01438-9
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1083/jcb.202211025

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  21. Dec 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells
    1
    1. scibot 23 Dec 2023
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      DOI: 10.1016/j.isci.2023.108645

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    Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation
    1
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      DOI: 10.1016/j.celrep.2023.113522

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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    1. scibot 20 Dec 2023
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      DOI: 10.1158/0008-5472.CAN-23-1065

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  25. 52.53.155.43 52.53.155.43
    can-23-1065-html.html
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    1. scibot 01 Dec 2023
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      DOI: 10.1158/0008-5472.can-23-1065

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      DOI: 10.1158/0008-5472.can-23-1065

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  26. Oct 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1016/j.isci.2023.108091

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  28. Sep 2023
  29. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
    1
    1. scibot 22 Sep 2023
      RRID:AB_11042766

      DOI: 10.1038/s41422-023-00874-4

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1016/j.isci.2023.107505

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  31. Aug 2023
  32. 52.53.155.43 52.53.155.43
    PIIS221112472300952X-html.html
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112941

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  33. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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      DOI: 10.1016/j.celrep.2023.112944

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  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112851

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ferroptosis activity is associated with neurological recovery following chronic compressive spinal cord injury
    1
    1. scibot 25 Jul 2023
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      DOI: 10.4103/1673-5374.371378

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    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice
    1
    1. scibot 08 Jul 2023
      RRID:AB_2916274

      DOI: 10.7150/ijbs.78489

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  39. www.embopress.org www.embopress.org
    Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics
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      DOI: 10.15252/embr.202256538

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    embopress.org/doi/full/10.15252/embr.202256538
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.022

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    sciencedirect.com/science/article/pii/S1097276523003787
  42. www.sciencedirect.com www.sciencedirect.com
    IL-17C neutralization protects the kidney against acute injury and chronic injury
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      DOI: 10.1016/j.ebiom.2023.104607

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  43. May 2023
  44. 52.53.155.43 52.53.155.43
    mcr-22-1012-html.html
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      DOI: 10.1158/1541-7786.mcr-22-1012

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  45. www.nature.com www.nature.com
    Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus
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      DOI: 10.1038/s41420-023-01445-7

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  46. Apr 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
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      DOI: 10.1016/j.neuron.2023.04.006

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    sciencedirect.com/science/article/pii/S0896627323002684
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    RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits
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      DOI: 10.1016/j.molcel.2023.02.028

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    sciencedirect.com/science/article/pii/S1097276523001557
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    The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112349

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    sciencedirect.com/science/article/pii/S2211124723003601
  50. Mar 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
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      DOI: 10.1016/j.devcel.2023.02.006

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    sciencedirect.com/science/article/pii/S1534580723000485
  52. Jan 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion
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    1. scibot 11 Jan 2023
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      DOI: 10.4103/1673-5374.355821

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  54. Dec 2022
  55. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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      RRID:AB_11042766

      DOI: 10.15252/embj.2022111961

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      DOI: 10.15252/embj.2022111961

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  56. Nov 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease
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      RRID:AB_11042766

      DOI: 10.1016/j.neuron.2022.10.021

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  58. Oct 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia
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      DOI: 10.1016/j.isci.2022.105263

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  60. Sep 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity
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  62. Aug 2022
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    Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis
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  64. May 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function
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  68. Apr 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    Recycling of autophagosomal components from autolysosomes by the recycler complex
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  72. Mar 2022
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    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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  75. Oct 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium
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  77. Aug 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Methylation of dual-specificity phosphatase 4 controls cell differentiation
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  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low‐dose cisplatin exposure
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  80. Jul 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense
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  82. academic.oup.com academic.oup.com
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      DOI: 10.1210/en.2018-00887

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  84. Jun 2021
  85. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
    1
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      DOI: 10.1016/j.ebiom.2021.103441

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  86. May 2021
  87. journals.biologists.com journals.biologists.com
    Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor
    1
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      RRID:AB_11042766

      DOI: 10.1242/dev.194787

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  88. www.sciencedirect.com www.sciencedirect.com
    Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis
    1
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      DOI: 10.1016/j.immuni.2020.06.004

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  89. Apr 2021
  90. www.cell.com www.cell.com
    Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
    1
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      DOI: 10.1016/j.cmet.2021.04.001

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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00167-4
  91. Dec 2020
  92. www.sciencedirect.com www.sciencedirect.com
    CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
    1
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      RRID:AB_11042766

      DOI: 10.1016/j.phrs.2020.105333

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  93. Sep 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
    1
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      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2020.02.090

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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
    1
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      RRID:AB_11042766

      DOI: 10.1016/j.celrep.2019.12.056

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  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐127‐5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency
    1
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      DOI: 10.1002/jcp.29725

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    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
    1
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      RRID:AB_11042766

      DOI: 10.1016/j.molcel.2020.06.017

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  98. Jan 2020
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic HKDC1 Expression Contributes to Liver Metabolism
    1
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      RRID:AB_11042766

      DOI: 10.1210/en.2018-00887

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
    1
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      DOI: 10.7554/eLife.50850

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  101. academic.oup.com academic.oup.com
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  103. Nov 2018
  104. www.sciencedirect.com www.sciencedirect.com
    BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation
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    Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
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  108. europepmc.org europepmc.org
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  109. Nov 2017
  110. academic.oup.com academic.oup.com
    IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells
    1
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