76 Matching Annotations
  1. Last 7 days
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    The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection
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    sciencedirect.com/science/article/pii/S0925443924001820
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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    1. scibot 10 Apr 2024
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      DOI: 10.7554/eLife.96891

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    ncbi.nlm.nih.gov/pmc/articles/PMC11001299/
  5. Mar 2024
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    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951324/
  7. Nov 2023
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    Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice
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    sciencedirect.com/science/article/pii/S2589004223023465
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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    sciencedirect.com/science/article/pii/S1074761323004181
  10. Oct 2023
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    The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers
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    52.53.155.43/e45e39aa6be90d4518c1365e2458466145a6420b/2023.06.16.545259v2.full-html.html
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    ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer
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      DOI: 10.7554/eLife.85898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541180/
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    ZEB2 and MEIS1 independently contribute to hematopoiesis via early hematopoietic enhancer activation
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    sciencedirect.com/science/article/pii/S2589004223019703
  14. Sep 2023
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    Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction
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    1. scibot 30 Sep 2023
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    sciencedirect.com/science/article/pii/S2211124723011889
  16. Jul 2023
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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    sciencedirect.com/science/article/pii/S2211124723008161
  18. May 2023
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    Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis
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    1. scibot 17 May 2023
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    sciencedirect.com/science/article/pii/S1097276523002137
  20. Apr 2023
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    Actionable spontaneous antibody responses antagonize malignant progression in ovarian carcinoma
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    1. scibot 29 Apr 2023
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    sciencedirect.com/science/article/pii/S0090825823001671
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    Decoding the molecular crosstalk between grafted stem cells and the stroke-injured brain
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    sciencedirect.com/science/article/pii/S2211124723003649
  23. Mar 2023
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    Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery
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    europepmc.org/article/med/36921598
  25. Jan 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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      DOI: 10.26508/lsa.202201457

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    ncbi.nlm.nih.gov/pmc/articles/PMC9834662/
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    Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors
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      DOI: 10.1158/1535-7163.MCT-21-0872

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    ncbi.nlm.nih.gov/pmc/articles/PMC9256805/
  28. Nov 2022
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    Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis
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      DOI: 10.1126/sciimmunol.abm9811

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    science.org/doi/10.1126/sciimmunol.abm9811
  30. Oct 2022
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    MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
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    sciencedirect.com/science/article/pii/S2211124722012864
  32. Aug 2022
  33. www.cell.com www.cell.com
    Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
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      DOI: 10.1016/j.stem.2022.08.002

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    cell.com/cell-stem-cell/fulltext/S1934-5909(22)00338-1
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    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
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      DOI: 10.1002/brb3.2736

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    onlinelibrary.wiley.com/doi/10.1002/brb3.2736
  35. Jul 2022
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    Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2211124722009342
  37. Jun 2022
  38. 52.53.155.43 52.53.155.43
    mct-21-0872-html.html
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    Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
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    sciencedirect.com/science/article/pii/S1550413122001863
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    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
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      DOI: 10.1016/j.neuron.2022.05.009

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    sciencedirect.com/science/article/pii/S0896627322004500
  41. Mar 2022
  42. www.sciencedirect.com www.sciencedirect.com
    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413122000547
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    Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism
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    sciencedirect.com/science/article/pii/S2211124722002248
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    CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4
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      DOI: 10.1016/j.ccell.2022.02.003

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    sciencedirect.com/science/article/pii/S1535610822000368
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    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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    sciencedirect.com/science/article/pii/S2211124722001474
  46. Feb 2022
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    Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
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    sciencedirect.com/science/article/pii/S1931312822000427
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Efferocytosis induces macrophage proliferation to help resolve tissue injury
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    sciencedirect.com/science/article/pii/S1550413121005271
  50. Oct 2021
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    GCN2 adapts protein synthesis to scavenging-dependent growth
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    sciencedirect.com/science/article/pii/S2405471221003823
  52. Aug 2021
  53. www.nature.com www.nature.com
    The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core
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      DOI: 10.1038/s41467-021-25200-7

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    nature.com/articles/s41467-021-25200-7
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
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      DOI: 10.7554/eLife.59654

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    ncbi.nlm.nih.gov/pmc/articles/PMC8346284/
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    ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes
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      DOI: 10.1016/j.celrep.2018.11.030

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    sciencedirect.com/science/article/pii/S2211124718317765
  56. Jul 2021
  57. www.sciencedirect.com www.sciencedirect.com
    An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors
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      DOI: 10.1016/j.ebiom.2016.06.007

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    sciencedirect.com/science/article/pii/S2352396416302511
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    Macrophage and neutrophil death programs differentially confer resistance to tuberculosis
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      DOI: 10.1016/j.immuni.2021.06.009

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    sciencedirect.com/science/article/pii/S1074761321002533
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFAT signaling in human mesenchymal stromal cells affects extracellular matrix remodeling and antifungal immune responses
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      DOI: 10.1016/j.isci.2021.102683

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    ncbi.nlm.nih.gov/pmc/articles/PMC8233198/
  60. May 2021
  61. www.sciencedirect.com www.sciencedirect.com
    NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells
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      DOI: 10.1016/j.xcrm.2021.100279

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    sciencedirect.com/science/article/pii/S2666379121001075
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    Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling
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    HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells
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    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
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    High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers
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  91. Nov 2018
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    Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation
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    Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis
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    Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?
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    Overcoming Resistance to Targeted Anticancer Therapies through Small-Molecule-Mediated MEK Degradation
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    USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-dependent Protein Levels
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    mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
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    A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms
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    Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
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    Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
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    Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation: Endocrinology: Vol 157, No 12
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