72 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.devcel.2020.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
  3. Jun 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114316

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    sciencedirect.com/science/article/pii/S2211124724006442
  5. May 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    No Evidence of Sensory Neuropathy in a Traditional Mouse Model of Idiopathic Parkinson’s Disease
    1
    1. scibot 30 May 2024
      RRID:AB_2134500

      DOI: 10.3390/cells13100799

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    ncbi.nlm.nih.gov/pmc/articles/PMC11120514/
  7. 52.53.155.43 52.53.155.43
    No Evidence Of Sensory Neuropathy In A Traditional Mouse Model Of Idiopathic Parkinson’s Disease
    1
    1. scibot 17 May 2024
      RRID:AB_2134500

      DOI: 10.20944/preprints202403.0625.v1

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    52.53.155.43/d331407b38b5ae3727f61a4bfd2545dc01b879fe/preprints202403.0625.v1-html.html
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
    1
    1. scibot 30 Apr 2024
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
  10. Mar 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.006

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    sciencedirect.com/science/article/pii/S1097276524001254
  12. elifesciences.org elifesciences.org
    Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
    2
    1. scibot 01 Mar 2024
      RRID:AB_2134500

      DOI: 10.7554/eLife.89453

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    2. scibot 01 Mar 2024
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      DOI: 10.7554/eLife.89453

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    elifesciences.org/articles/89453
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
    1
    1. scibot 07 Dec 2023
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2023.113529

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    sciencedirect.com/science/article/pii/S2211124723015413
  15. Nov 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
    1
    1. scibot 17 Nov 2023
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2023.113436

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    sciencedirect.com/science/article/pii/S2211124723014481
  17. www.sciencedirect.com www.sciencedirect.com
    Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum
    1
    1. scibot 02 Nov 2023
      AB_528127

      DOI: 10.1016/j.isci.2023.108144

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    sciencedirect.com/science/article/pii/S2589004223022216
  18. Oct 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dopaminergic Input Regulates the Sensitivity of Indirect Pathway Striatal Spiny Neurons to Brain-Derived Neurotrophic Factor
    1
    1. scibot 31 Oct 2023
      RRID:AB_528127

      DOI: 10.3390/biology12101360

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    ncbi.nlm.nih.gov/pmc/articles/PMC10604681/
  20. Sep 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice
    1
    1. scibot 20 Sep 2023
      RRID:AB_2134500

      DOI: 10.1038/s41467-023-41502-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10505217/
  22. www.sciencedirect.com www.sciencedirect.com
    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
    1
    1. scibot 01 Sep 2023
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2023.113042

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    sciencedirect.com/science/article/pii/S2211124723010537
  23. May 2023
  24. www.sciencedirect.com www.sciencedirect.com
    DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons
    1
    1. scibot 31 May 2023
      RRID:AB_528127

      DOI: 10.1016/j.celrep.2023.112575

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    sciencedirect.com/science/article/pii/S2211124723005867
  25. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  26. insight.jci.org insight.jci.org
    Immune landscape of a genetically engineered murine model of glioma compared to human glioma by single-cell sequencing
    1
    1. scibot 06 May 2023
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      DOI: 10.1172/jci.insight.148990

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    insight.jci.org/articles/view/148990
  27. Apr 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 09 Apr 2023
      RRID:AB_528127

      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  29. Dec 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111862

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    sciencedirect.com/science/article/pii/S2211124722017582
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
    1
    1. scibot 16 Dec 2022
      RRID:AB_2134500

      DOI: 10.3389/fnmol.2022.1069122

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    ncbi.nlm.nih.gov/pmc/articles/PMC9749902/
  32. Nov 2022
  33. www.molbiolcell.org www.molbiolcell.org
    Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events and slow maturation
    1
    1. scibot 17 Nov 2022
      AB_2134500

      DOI: 10.1091/mbc.E22-03-0111

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    molbiolcell.org/doi/10.1091/mbc.E22-03-0111
  34. www.sciencedirect.com www.sciencedirect.com
    TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
    1
    1. scibot 11 Nov 2022
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      DOI: 10.1016/j.neuron.2022.10.022

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    sciencedirect.com/science/article/pii/S0896627322009552
  35. May 2022
  36. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 imposes the reserve stem cell state of gastric chief cells
    1
    1. scibot 06 May 2022
      RRID:AB_2134500

      DOI: 10.1016/j.stem.2022.04.001

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    sciencedirect.com/science/article/pii/S1934590922001540
  37. Jan 2022
  38. www.nature.com www.nature.com
    Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes
    1
    1. scibot 22 Jan 2022
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      DOI: 10.1038/s41596-021-00638-7

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    nature.com/articles/s41596-021-00638-7
  39. www.sciencedirect.com www.sciencedirect.com
    Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting
    1
    1. scibot 14 Jan 2022
      RRID:AB_2134500

      DOI: 10.1016/j.isci.2021.103715

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    sciencedirect.com/science/article/pii/S2589004221016850
  40. www.sciencedirect.com www.sciencedirect.com
    Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
    1
    1. scibot 05 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110187

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    sciencedirect.com/science/article/pii/S2211124721016879
  41. Nov 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Stabilin receptors clear LPS and control systemic inflammation
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103337

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    sciencedirect.com/science/article/pii/S2589004221013067
  43. Aug 2021
  44. www.embopress.org www.embopress.org
    A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication
    1
    1. scibot 31 Aug 2021
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      DOI: 10.15252/embj.2021107664

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    embopress.org/doi/abs/10.15252/embj.2021107664
  45. jcb.rupress.org jcb.rupress.org
    Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes
    1
    1. scibot 14 Aug 2021
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      DOI: 10.1083/jcb.201711039

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    jcb.rupress.org/content/217/9/3141
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.neuron.2017.01.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC5340420/
  47. www.jneurosci.org www.jneurosci.org
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      DOI: 10.1523/JNEUROSCI.0632-14.2015

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    jneurosci.org/content/35/14/5724
  48. europepmc.org europepmc.org
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      DOI: 10.7554/eLife.40856

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    europepmc.org/articles/PMC6292694/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1093/hmg/ddx321

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    ncbi.nlm.nih.gov/pmc/articles/PMC5886073/
  50. Jul 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
    1
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      DOI: 10.1016/j.chom.2018.10.005

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    sciencedirect.com/science/article/pii/S1931312818305432
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.09.065

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    ncbi.nlm.nih.gov/pmc/articles/PMC6280974/
  53. www.sciencedirect.com www.sciencedirect.com
    A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication
    2
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      DOI: 10.1016/j.chom.2017.07.017

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      DOI: 10.1016/j.chom.2017.07.017

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    sciencedirect.com/science/article/pii/S1931312817303001
  54. Jun 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology
    1
    1. scibot 09 Jun 2021
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2021.109228

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    sciencedirect.com/science/article/pii/S2211124721005799
  56. May 2021
  57. www.tandfonline.com www.tandfonline.com
    CREG1 promotes lysosomal biogenesis and function
    2
    1. scibot 15 May 2021
      RRID:AB_528127

      DOI: 10.1080/15548627.2021.1909997

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      DOI: 10.1080/15548627.2021.1909997

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    tandfonline.com/doi/abs/10.1080/15548627.2021.1909997
  58. www.sciencedirect.com www.sciencedirect.com
    Microglia Do Not Take Up Soluble Amyloid-beta Peptides, But Partially Degrade Them by Secreting Insulin-degrading Enzyme
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.neuroscience.2020.07.020

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    sciencedirect.com/science/article/pii/S030645222030453X
  59. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
    1
    1. scibot 06 May 2021
      RRID:AB_2134500

      DOI: 10.1016/j.devcel.2021.01.016

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    sciencedirect.com/science/article/pii/S1534580721000745
  60. www.sciencedirect.com www.sciencedirect.com
    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
    1
    1. scibot 06 May 2021
      RRID:AB_2134500

      DOI: 10.1016/j.devcel.2020.11.016

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    sciencedirect.com/science/article/pii/S1534580720309254
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
    1
    1. scibot 05 May 2021
      RRID:AB_528127

      DOI: 10.1016/j.devcel.2020.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
    1
    1. scibot 28 Apr 2021
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2021.109034

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    sciencedirect.com/science/article/pii/S2211124721003508
  64. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
    1
    1. scibot 23 Apr 2021
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      DOI: 10.1016/j.cell.2021.03.048

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    sciencedirect.com/science/article/pii/S0092867421003792
  65. www.sciencedirect.com www.sciencedirect.com
    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
    1
    1. scibot 20 Apr 2021
      RRID:AB_2134500

      DOI: 10.1016/j.devcel.2021.03.032

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    sciencedirect.com/science/article/pii/S1534580721003075
  66. Dec 2020
  67. www.cell.com www.cell.com
    Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection
    1
    1. scibot 11 Dec 2020
      RRID:AB_528127

      DOI: 10.1016/j.chom.2020.09.004

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    cell.com/cell-host-microbe/fulltext/S1931-3128(20)30505-9
  68. Oct 2020
  69. www.jneurosci.org www.jneurosci.org
    14,15-epoxyeicosatrienoic acid alleviates pathology in a mouse model of Alzheimer’s disease
    1
    1. scibot 22 Oct 2020
      RRID:AB_2134500

      DOI: 10.1523/JNEUROSCI.1246-20.2020

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    jneurosci.org/content/40/42/8188
  70. Sep 2020
  71. www.sciencedirect.com www.sciencedirect.com
    The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network
    1
    1. scibot 16 Sep 2020
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2020.107614

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    sciencedirect.com/science/article/pii/S2211124720305635
  72. www.sciencedirect.com www.sciencedirect.com
    Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation
    1
    1. scibot 12 Sep 2020
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2020.107721

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    sciencedirect.com/science/article/pii/S2211124720306987
  73. www.sciencedirect.com www.sciencedirect.com
    The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons
    1
    1. scibot 06 Sep 2020
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2020.02.060

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    sciencedirect.com/science/article/pii/S221112472030228X
  74. www.sciencedirect.com www.sciencedirect.com
    Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
    1
    1. scibot 05 Sep 2020
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2020.107775

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    sciencedirect.com/science/article/pii/S2211124720307555
  75. Jan 2020
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hemozoin produced by mammals confers heme tolerance
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.7554/eLife.49503

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    ncbi.nlm.nih.gov/pmc/articles/PMC6773446/
  77. www.jneurosci.org www.jneurosci.org
    Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.1523/JNEUROSCI.3069-18.2019

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    jneurosci.org/content/39/23/4606
  78. elifesciences.org elifesciences.org
    A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits
    1
    1. scibot 13 Jan 2020
      RRID:AB_528127

      DOI: 10.7554/eLife.49253

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    elifesciences.org/articles/49253
  79. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.1016/j.celrep.2019.02.103

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    sciencedirect.com/science/article/pii/S221112471930289X
  80. www.sciencedirect.com www.sciencedirect.com
    ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.1016/j.molcel.2019.03.027

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    sciencedirect.com/science/article/pii/S109727651930231X
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.7554/eLife.40856

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    ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
  82. www.jneurosci.org www.jneurosci.org
    The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2
    1
    1. scibot 13 Jan 2020
      RRID:AB_2134500

      DOI: 10.1523/JNEUROSCI.2811-18.2019

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    jneurosci.org/content/39/18/3376
  83. Nov 2018
  84. www.nature.com www.nature.com
    Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
    1
    1. scibot 05 Nov 2018
      AB_528127

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    nature.com/articles/ncb3631
  85. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2134500

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    sciencedirect.com/science/article/pii/S2211124718315250
  86. www.sciencedirect.com www.sciencedirect.com
    Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1
    1
    1. scibot 05 Nov 2018
      RRID:AB_2134500

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    sciencedirect.com/science/article/pii/S1550413118303309
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages
    1
    1. scibot 05 Nov 2018
      RRID:AB_2134500

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    onlinelibrary.wiley.com/doi/full/10.1111/tra.12552
  88. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2134500

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    academic.oup.com/hmg/article/26/22/4352/4082708
  89. Nov 2017
  90. academic.oup.com academic.oup.com
    Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer’s disease neurons
    1
    1. scibot 08 Nov 2017
      RRID:AB_2134500

      Curator: @patriciaelyse_

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    academic.oup.com/hmg/article/doi/10.1093/hmg/ddx321/4082708/Impaired-axonal-retrograde-trafficking-of-the
  91. www.sciencedirect.com www.sciencedirect.com
    TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss
    1
    1. scibot 08 Nov 2017
      AB_2134500

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0896627317304750
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
    1
    1. scibot 08 Nov 2017
      anti-LAMP1

      Curator: @chewbeccax

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    ncbi.nlm.nih.gov/pmc/articles/PMC5127638/
  93. www.sciencedirect.com www.sciencedirect.com
    Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons
    1
    1. scibot 08 Nov 2017
      AB_2134500

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0896627317300430
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2
    1
    1. scibot 08 Nov 2017
      AB_2134500

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC4388928/
  95. Dec 2015
  96. www.jneurosci.org www.jneurosci.org
    Untitled document
    1
    1. judell 21 Dec 2015
      AB_2134500

      Antibody ID: AB_2134500

      Target Antigen: Lamp1 See NCBI gene

      Vendor: DSHB

      Cat Num: 1D4B

      Proper Citation: (DSHB Cat# 1D4B, RRID:AB_2134500)

      Reference: PMID:21344404

      Clonality: monoclonal antibody

      Clone ID: None

      Host Organism: rat

      Comments: Useful for western blot mouse

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    jneurosci.org/content/35/14/5724.long
  97. www.jneurosci.org www.jneurosci.org
    Untitled document
    1
    1. judell 17 Dec 2015
      AB_2134500

      Antibody ID: AB_2134500

      Target Antigen: Lamp1 See NCBI gene

      Vendor: DSHB

      Cat Num: 1D4B

      Proper Citation: (DSHB Cat# 1D4B, RRID:AB_2134500)

      Reference: PMID:21344404

      Clonality: monoclonal antibody

      Clone ID: None

      Host Organism: rat

      Comments: Useful for western blot mouse

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      RRID:AB_2134500
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    jneurosci.org/content/35/14/5724.full