135 Matching Annotations
  1. Last 7 days
  2. www.nature.com www.nature.com
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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    1. scibot 18 Jul 2024
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  3. Jun 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
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    sciencedirect.com/science/article/pii/S1550413124001864
  5. May 2024
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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  7. Apr 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  9. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin
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      DOI: 10.1111/bph.16354

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16354
  10. www.nature.com www.nature.com
    Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction
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    1. scibot 10 Apr 2024
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  11. Mar 2024
  12. www.biorxiv.org www.biorxiv.org
    Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis
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    1. scibot 21 Mar 2024
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    biorxiv.org/content/10.1101/2024.02.29.582877v1
  13. Feb 2024
  14. 52.53.155.43 52.53.155.43
    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
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    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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    1. scibot 14 Feb 2024
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  16. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
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  17. Jan 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue
    1
    1. scibot 26 Jan 2024
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      DOI: 10.3389/fimmu.2023.1308456

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803534/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1158/2767-9764.CRC-23-0275

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    ncbi.nlm.nih.gov/pmc/articles/PMC10793200/
  20. Dec 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner
    1
    1. scibot 13 Dec 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10710518/
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    MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle
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    sciencedirect.com/science/article/pii/S2211124723014778
  23. Nov 2023
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    Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
    1
    1. scibot 29 Nov 2023
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    sciencedirect.com/science/article/pii/S2589004223023556
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    Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice
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    sciencedirect.com/science/article/pii/S2589004223023465
  26. Oct 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.chembiol.2023.09.017

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    sciencedirect.com/science/article/pii/S2451945623003367
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    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
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    sciencedirect.com/science/article/pii/S1550413123003686
  29. Sep 2023
  30. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
    1
    1. scibot 22 Sep 2023
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    nature.com/articles/s41422-023-00874-4
  31. Aug 2023
  32. 52.53.155.43 52.53.155.43
    LINC00116-Encoded Microprotein Mitoregulin Regulates Fatty Acid Metabolism at the Mitochondrial Outer Membrane
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    52.53.155.43/059bf8b11a4bdbbc7113047ac5328dabaca7c676/PIIS2589004223016358-html.html
  33. 52.53.155.43 52.53.155.43
    Hypothalamic astrocytic-BMAL1 regulates energy homeostasis in a sex-dependent manner
    3
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    52.53.155.43/38afd9540d2c9d024b7feab1dc4203b0cfc9e994/PIIS2211124723009609-html.html
  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Increased Cardiac PFK-2 Protects Against High-Fat Diet-Induced Cardiomyopathy and Mediates Beneficial Systemic Metabolic Effects
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    sciencedirect.com/science/article/pii/S2589004223012087
  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity
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    sciencedirect.com/science/article/pii/S155041312300178X
  38. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
    1
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      DOI: 10.1016/j.isci.2023.106791

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    sciencedirect.com/science/article/pii/S2589004223008684
  39. Apr 2023
  40. academic.oup.com academic.oup.com
    Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice
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    1. scibot 21 Apr 2023
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      DOI: 10.1210/endocr/bqad034

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    academic.oup.com/endo/article/164/4/bqad034/7045509
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    Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
    1
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    sciencedirect.com/science/article/pii/S2211124723003303
  42. Mar 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10005909/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  45. Feb 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle
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    sciencedirect.com/science/article/pii/S1534580723000382
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    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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    sciencedirect.com/science/article/pii/S1567724922001088
  48. Jan 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
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    sciencedirect.com/science/article/pii/S2211124722018423
  50. Dec 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
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    sciencedirect.com/science/article/pii/S2211124722017582
  52. Nov 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
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      DOI: 10.1016/j.molcel.2022.10.030

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    sciencedirect.com/science/article/pii/S1097276522010589
  54. www.sciencedirect.com www.sciencedirect.com
    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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      DOI: 10.1016/j.molcel.2022.10.026

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    sciencedirect.com/science/article/pii/S1097276522010541
  55. Oct 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
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    sciencedirect.com/science/article/pii/S2211124722012761
  57. Aug 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
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    Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis
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  60. Jul 2022
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    Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
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    Protein signaling in response to ex vivo dynamic contractions is independent of training status in rat skeletal muscle
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  64. Jun 2022
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  66. May 2022
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    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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  68. Mar 2022
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    Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
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    The Alzheimer’s disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
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    AMPK ACTIVATION AMELIORATES KIDNEY VASCULAR DYSFUNCTION, OXIDATIVE STRESS AND INFLAMMATION IN OBESITY
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  98. Jul 2021
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    Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
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      Rabbit polyclonal Anti-pACC/TotACC

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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
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    Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health
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    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle
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    PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
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    ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism
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      polyclonal rabbit phospho-acetyl-coa carboxylase

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  133. Jan 2020
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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  146. Nov 2018
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    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
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    The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
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    Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling
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    Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
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    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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    Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis
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    Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERRATUM FOR “α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet–Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling”
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      AB_330337

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6790524/
  161. academic.oup.com academic.oup.com
    α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet–Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling
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    1. scibot 05 Nov 2018
      AB_330337

      Curator: @evieth

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    academic.oup.com/endo/article/159/2/931/4764022
  162. www.sciencedirect.com www.sciencedirect.com
    PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs
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    sciencedirect.com/science/article/pii/S1550413117305570
  163. Nov 2017
  164. academic.oup.com academic.oup.com
    Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice
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    1. scibot 08 Nov 2017
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    academic.oup.com/endo/article/158/10/3090/4082873/Antibody-Mediated-Targeting-of-the-FGFR1c-Isoform
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    1. scibot 08 Nov 2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC5501726/table/undtbl1/
  166. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    1. scibot 08 Nov 2017
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      Curator: @chewbeccax

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  167. academic.oup.com academic.oup.com
    3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice
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    1. scibot 08 Nov 2017
      AB_330337

      Curator: @bandrow

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    academic.oup.com/endo/article/158/6/1977/3078999/3-Iodothyronamine-Induces-Tail-Vasodilation
  168. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  169. www.sciencedirect.com www.sciencedirect.com
    DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging
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      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1550413117302139
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
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    1. scibot 08 Nov 2017
      3661

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC4931344/
  171. elifesciences.org elifesciences.org
    SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise
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    1. scibot 08 Nov 2017
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      Curator: @gabimpine

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    elifesciences.org/articles/18206
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy
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    1. scibot 08 Nov 2017
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      Curator: @jcabotaj

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    ncbi.nlm.nih.gov/pmc/articles/PMC4502912/