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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    sciencedirect.com/science/article/pii/S1097276524008657
  3. Sep 2024
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    Untitled document
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  5. Aug 2024
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    Highly specific σ<sub>2</sub>R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response
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      Cell Signaling #3661

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  7. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
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    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  9. Jul 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11263643/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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  12. Jun 2024
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    Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
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  14. May 2024
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  16. Apr 2024
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    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin
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    Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction
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  20. Mar 2024
  21. www.biorxiv.org www.biorxiv.org
    Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis
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  22. Feb 2024
  23. 52.53.155.43 52.53.155.43
    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
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    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  26. Jan 2024
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    CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793200/
  29. Dec 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10710518/
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    MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle
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    sciencedirect.com/science/article/pii/S2211124723014778
  32. Nov 2023
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    Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
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    Macrophage AMPK β1 activation by PF-06409577 reduces the inflammatory response, cholesterol synthesis, and atherosclerosis in mice
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  35. Oct 2023
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    Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
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    sciencedirect.com/science/article/pii/S2451945623003367
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    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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    sciencedirect.com/science/article/pii/S1550413123003686
  38. Sep 2023
  39. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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  40. Aug 2023
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    LINC00116-Encoded Microprotein Mitoregulin Regulates Fatty Acid Metabolism at the Mitochondrial Outer Membrane
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  42. 52.53.155.43 52.53.155.43
    Hypothalamic astrocytic-BMAL1 regulates energy homeostasis in a sex-dependent manner
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  43. Jul 2023
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    Increased Cardiac PFK-2 Protects Against High-Fat Diet-Induced Cardiomyopathy and Mediates Beneficial Systemic Metabolic Effects
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    sciencedirect.com/science/article/pii/S2589004223012087
  45. May 2023
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    Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity
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    sciencedirect.com/science/article/pii/S155041312300178X
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    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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    sciencedirect.com/science/article/pii/S2589004223008684
  48. Apr 2023
  49. academic.oup.com academic.oup.com
    Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice
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      DOI: 10.1210/endocr/bqad034

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    academic.oup.com/endo/article/164/4/bqad034/7045509
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    Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
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    sciencedirect.com/science/article/pii/S2211124723003303
  51. Mar 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10005909/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  54. Feb 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle
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    sciencedirect.com/science/article/pii/S1534580723000382
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    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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    sciencedirect.com/science/article/pii/S1567724922001088
  57. Jan 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
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  59. Dec 2022
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    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
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  61. Nov 2022
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    Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
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    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
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  66. Aug 2022
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    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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  69. Jul 2022
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    Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
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    Protein signaling in response to ex vivo dynamic contractions is independent of training status in rat skeletal muscle
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  73. Jun 2022
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    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
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  75. May 2022
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    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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  77. Mar 2022
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    Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
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  84. Jan 2022
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    The Alzheimer’s disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  87. Dec 2021
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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  90. Nov 2021
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    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
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  93. Oct 2021
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    Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
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  95. Sep 2021
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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  99. Aug 2021
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    AMPK ACTIVATION AMELIORATES KIDNEY VASCULAR DYSFUNCTION, OXIDATIVE STRESS AND INFLAMMATION IN OBESITY
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    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  107. Jul 2021
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    Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
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      Rabbit polyclonal Anti-pACC/TotACC

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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
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    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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  114. May 2021
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    Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health
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  120. Feb 2021
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    Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner | American Journal of Physiology-Endocrinology and Metabolism
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      polyclonal rabbit phospho-acetyl-coa carboxylase

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    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
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  142. Jan 2020
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
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    Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
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    Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2
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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan
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    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
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  163. www.sciencedirect.com www.sciencedirect.com
    Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling
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    sciencedirect.com/science/article/pii/S1550413118303887
  164. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
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    sciencedirect.com/science/article/pii/S1550413117305703
  165. www.sciencedirect.com www.sciencedirect.com
    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  167. www.sciencedirect.com www.sciencedirect.com
    Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis
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    sciencedirect.com/science/article/pii/S0303720718301242
  168. www.sciencedirect.com www.sciencedirect.com
    Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERRATUM FOR “α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet–Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling”
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      Curator: @evieth

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  170. academic.oup.com academic.oup.com
    α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet–Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling
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  171. www.sciencedirect.com www.sciencedirect.com
    PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs
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  172. Nov 2017
  173. academic.oup.com academic.oup.com
    Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC5501726/table/undtbl1/
  175. www.sciencedirect.com www.sciencedirect.com
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
    1
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      Curator: @chewbeccax

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  176. academic.oup.com academic.oup.com
    3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice
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      Curator: @bandrow

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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  178. www.sciencedirect.com www.sciencedirect.com
    DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging
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      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1550413117302139
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
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      3661

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    ncbi.nlm.nih.gov/pmc/articles/PMC4931344/
  180. elifesciences.org elifesciences.org
    SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise
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    elifesciences.org/articles/18206
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy
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      Curator: @jcabotaj

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    ncbi.nlm.nih.gov/pmc/articles/PMC4502912/