Hypothesis

95 Matching Annotations

May 2026
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Synaptic attenuation by human alpha-synuclein depends on two amino acids in its C-terminal tail

1
1. scibot 06 May 2026
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.nbd.2026.107437
  
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sciencedirect.com/science/article/pii/S0969996126001828
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Peptide-Mediated Delivery of α-Synuclein Targeting ASO: Pharmacokinetics, Safety, and CNS Efficacy in a Synucleinopathy Model

1
1. scibot 21 Apr 2026
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.dmd.2026.100304
  
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sciencedirect.com/science/article/pii/S0090955626000735
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Stochastic misfolding drives the emergence of distinct α-synuclein strains

1
1. scibot 03 Mar 2026
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.neuron.2026.01.014
  
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sciencedirect.com/science/article/pii/S0896627326000401
Feb 2026
www.science.org www.science.org

α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction

1
1. scibot 03 Feb 2026
  
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  RRID:AB_398107
  
  DOI: 10.1126/sciadv.ady6978
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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science.org/doi/10.1126/sciadv.ady6978
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction

1
1. scibot 30 Jan 2026
  
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  RRID:AB_398107
  
  DOI: 10.1126/sciadv.ady6978
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12851034/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

1
1. scibot 16 Jul 2025
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.celrep.2025.115636
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12258067/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease

1
1. scibot 15 Jun 2025
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.celrep.2025.115355
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12124131/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits

1
1. scibot 19 Apr 2025
  
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  RRID:AB_398107
  
  DOI: 10.1523/ENEURO.0357-24.2025
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11998964/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

1
1. scibot 16 Apr 2025
  
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  RRID:AB_398107
  
  DOI: 10.1126/sciadv.adq2519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980859/
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 03 Apr 2025
  
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  RRID:AB_398107
  
  DOI: 10.1523/eneuro.0357-24.2025
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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52.53.155.43/6343470ab662b00750e766dae62c29226c242386/PDF-html.html
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease

1
1. scibot 11 Mar 2025
  
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  RRID:AB_398107
  
  DOI: 10.1016/j.celrep.2025.115355
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_398107
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12124131/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies

7
1. scibot 07 Feb 2025
  
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  AB_398107
  
  DOI: 10.21203/rs.3.rs-5649173/v1
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_398107
  
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  RRID:AB_398107
2. scibot 06 Feb 2025
  
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  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
3. scibot 05 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
4. scibot 04 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
5. scibot 03 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
6. scibot 02 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
7. scibot 01 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
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URL

pmc.ncbi.nlm.nih.gov/articles/PMC11703330/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies

7
1. scibot 07 Feb 2025
  
  in Public
  
  AB_398107
  
  DOI: 10.1101/2024.10.23.619548
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_398107
  
  What is this?
  
  RRID:AB_398107
2. scibot 06 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
3. scibot 05 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
4. scibot 04 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
5. scibot 03 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
6. scibot 02 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
7. scibot 01 Feb 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
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pmc.ncbi.nlm.nih.gov/articles/PMC11527026/
52.53.155.43 52.53.155.43

awaf051-html.html

1
1. scibot 07 Feb 2025
  
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  AB_398107
  
  DOI: 10.1093/brain/awaf051
  
  Resource: (BD Biosciences Cat# 610786, RRID:AB_398107)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_398107
  
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52.53.155.43/ad3dfd72e4bbedea4b2fe45e2acb356095b82879/awaf051-html.html
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies

8
1. scibot 31 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
2. scibot 30 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
3. scibot 29 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
4. scibot 28 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
5. scibot 27 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
6. scibot 26 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
7. scibot 25 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
8. scibot 24 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
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URL

pmc.ncbi.nlm.nih.gov/articles/PMC11703330/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies

16
1. scibot 31 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
2. scibot 30 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
3. scibot 29 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
4. scibot 28 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
5. scibot 27 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
6. scibot 26 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
7. scibot 25 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
8. scibot 24 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
9. scibot 23 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
10. scibot 22 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
11. scibot 21 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
12. scibot 20 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
13. scibot 19 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
14. scibot 18 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
15. scibot 17 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
16. scibot 16 Jan 2025
  
  in Public
  
  AB_398107
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_398107
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pmc.ncbi.nlm.nih.gov/articles/PMC11527026/
Jul 2024
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Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

1
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  AB_398107
  
  DOI: 10.1016/j.neuron.2024.06.002
  
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Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits

1
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  DOI: 10.1101/2024.07.09.602700
  
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biorxiv.org/content/10.1101/2024.07.09.602700v1
May 2024
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Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy

2
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  DOI: 10.1038/s41531-024-00679-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11109094/
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P. mirabilis-derived pore-forming haemolysin, HpmA drives intestinal alpha-synuclein aggregation in a mouse model of neurodegeneration

1
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  DOI: 10.1016/j.ebiom.2023.104887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10709029/
Jun 2023
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Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation

1
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  DOI: 10.1016/j.stem.2023.05.015
  
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Mar 2023
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Neuronal identity defines α-synuclein and tau toxicity

1
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Neuronopathic GBA1L444P mutation accelerates Glucosylsphingosine levels and formation of hippocampal alpha-synuclein inclusions

1
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pmc.ncbi.nlm.nih.gov/articles/PMC9864632/
Nov 2022
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Nicotine-Mediated Rescue of α-Synuclein Toxicity Requires Synaptic Vesicle Glycoprotein 2 in Drosophila

1
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movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29283
Jun 2022
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Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity

1
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  DOI: 10.3390/cancers14061382
  
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52.53.155.43/4deaece5f576ac127195ceba06752c88cfcd6756/cancers-14-01382-v2-html.html
May 2022
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PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease

1
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Nov 2021
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Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein

1
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  DOI: 10.1186/s40478-021-01283-7
  
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Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity

1
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Untitled document

1
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  DOI: 10.1523/JNEUROSCI.0632-14.2015
  
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jneurosci.org/content/35/14/5724
Jul 2021
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Untitled document

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  DOI: 10.1038/s41598-018-33474-z
  
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Untitled document

1
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  DOI: 10.1016/j.neuron.2017.01.019
  
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Glucosylsphingosine promotes α-synuclein pathology in mutant GBA-associated Parkinson's disease

3
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  DOI: 10.1523/JNEUROSCI.1525-17.2017
  
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jneurosci.org/content/37/40/9617
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Sensitivity and specificity of phospho‐Ser129 α‐synuclein monoclonal antibodies

1
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  DOI: 10.1002/cne.24468
  
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onlinelibrary.wiley.com/doi/full/10.1002/cne.24468
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Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α‐synuclein

1
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  DOI: 10.1002/jnr.23677
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23677/full
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Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model

1
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  DOI: 10.1002/jnr.24927
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24927
Jun 2021
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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

1
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  DOI: 10.1016/j.celrep.2021.109189
  
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sciencedirect.com/science/article/pii/S2211124721005350
Dec 2020
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Chronic MPTP in Mice Damage-specific Neuronal Phenotypes within Dorsal Laminae of the Spinal Cord

1
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link.springer.com/article/10.1007/s12640-020-00313-x
Nov 2020
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Distinct alpha‐Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH‐SY5Y cells

1
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  DOI: 10.1111/jnc.15174
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15174
Sep 2020
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Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis

1
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  DOI: 10.7554/eLife.58613
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7438114/
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Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

1
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  DOI: 10.1016/j.celrep.2019.12.078
  
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sciencedirect.com/science/article/pii/S2211124719317437
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Upregulating β-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity

1
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  DOI: 10.1186/s40478-020-01004-6
  
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link.springer.com/article/10.1186/s40478-020-01004-6
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H63D variant of the homeostatic iron regulator (HFE) gene alters α‐synuclein expression, aggregation, and toxicity

1
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onlinelibrary.wiley.com/doi/10.1111/jnc.15107
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Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior

1
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  DOI: 10.1016/j.celrep.2019.09.029
  
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Enhanced mitochondrial inhibition by 3,4‐dihydroxyphenyl‐acetaldehyde (DOPAL)‐oligomerized α‐synuclein

1
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  DOI: 10.1002/jnr.24513
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24513
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In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species

1
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sciencedirect.com/science/article/pii/S2211124719314111
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Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1038/s41598-019-54063-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6879756/
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Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

1
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  DOI: 10.1016/j.molcel.2018.11.028
  
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sciencedirect.com/science/article/pii/S1097276518309985
Nov 2018
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Lipid-dependent deposition of alpha-synuclein and Tau on neuronal Secretogranin II-positive vesicular membranes with age

1
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ncbi.nlm.nih.gov/pmc/articles/PMC6185981/
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A new model to study cell-to-cell transfer of αSynuclein in vivo

1
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sciencedirect.com/science/article/pii/S0006291X1831547X
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Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity

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1. scibot 05 Nov 2018
  
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  RRID:AB_398107
  
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sciencedirect.com/science/article/pii/S1097276517306652
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α-Synuclein-Dependent Calcium Entry Underlies Differential Sensitivity of Cultured SN and VTA Dopaminergic Neurons to a Parkinsonian Neurotoxin

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1. scibot 05 Nov 2018
  
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  RRID:AB_398107
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5701296/
europepmc.org europepmc.org

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1. scibot 05 Nov 2018
  
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  RRID:AB_398107
  
  Curator: @evieth
  
  Resource used:
  
  (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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europepmc.org/articles/PMC5701296/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons

1
1. scibot 08 Nov 2017
  
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  AB_398107
  
  Curator: @chewbeccax
  
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  (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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sciencedirect.com/science/article/pii/S0896627317300430
onlinelibrary.wiley.com onlinelibrary.wiley.com

Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated α‐synuclein

1
1. scibot 08 Nov 2017
  
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  AB_398107
  
  Curator: @gabimpine
  
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  (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24024/full
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MicroRNA-7 Protects against 1-Methyl-4-Phenylpyridinium-Induced Cell Death by Targeting RelA

1
1. scibot 08 Nov 2017
  
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  AB_398107
  
  Curator: @gabimpine
  
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  (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4166159/
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α-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2

1
1. scibot 08 Nov 2017
  
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  AB_398107
  
  Curator: @gabimpine
  
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  (BD Biosciences Cat# 610786, RRID:AB_398107)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4388928/
Dec 2015
www.jneurosci.org www.jneurosci.org

Untitled document

1
1. judell 21 Dec 2015
  
  in Public
  
  AB_398107
  
  Antibody ID: AB_398107
  Target Antigen: Synuclein, alpha See NCBI gene
  Vendor: BD Biosciences
  Cat Num: 610786
  Proper Citation: (BD Biosciences Cat# 610786, RRID:AB_398107)
  Reference: PMID:17099894
  Clonality: monoclonal antibody
  Clone ID: None
  Host Organism: mouse
  Comments: manufacturer recommendations: Immunofluorescence; Immunoprecipitation; Western Blot; IF, IP, WB human, mouse, rat
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jneurosci.org/content/35/14/5724.long
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Untitled document

1
1. judell 17 Dec 2015
  
  in Public
  
  AB_398107
  
  Antibody ID: AB_398107
  Target Antigen: Synuclein, alpha See NCBI gene
  Vendor: BD Biosciences
  Cat Num: 610786
  Proper Citation: (BD Biosciences Cat# 610786, RRID:AB_398107)
  Reference: PMID:17099894
  Clonality: monoclonal antibody
  Clone ID: None
  Host Organism: mouse
  Comments: manufacturer recommendations: Immunofluorescence; Immunoprecipitation; Western Blot; IF, IP, WB human, mouse, rat
  resolver lookup
  
  RRID:AB_398107
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jneurosci.org/content/35/14/5724.full

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