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Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

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1. scibot 03 Jul 2026
  
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  DOI: 10.1002/advs.76384
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76384
Jun 2026
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Bilirubin mitigates ischemic white matter injury by targeting transferrin-receptor-mediated B cell immunometabolism

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1. scibot 11 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117398
  
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sciencedirect.com/science/article/pii/S2211124726004766
May 2026
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117324
  
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sciencedirect.com/science/article/pii/S221112472600402X
Apr 2026
isevjournals.onlinelibrary.wiley.com isevjournals.onlinelibrary.wiley.com

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

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1. scibot 21 Apr 2026
  
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  DOI: 10.1002/jev2.70252
  
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isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev2.70252
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IL-4/IL-4Rα signaling activates PPARγ to promote oligodendrocyte differentiation and remyelination

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1. scibot 07 Apr 2026
  
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  DOI: 10.1016/j.bbi.2026.106568
  
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sciencedirect.com/science/article/pii/S0889159126003168
Jan 2026
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Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116840
  
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sciencedirect.com/science/article/pii/S2211124725016122
Dec 2025
54.241.53.176 54.241.53.176

A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.64898/2025.12.18.695023
  
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54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
Nov 2025
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

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1. scibot 13 Nov 2025
  
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  DOI: 10.1101/2025.11.06.687030
  
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
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Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy

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1. scibot 06 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102434
  
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sciencedirect.com/science/article/pii/S2666379125005075
Jun 2025
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Amitriptyline revitalizes ICB response via dually inhibiting Kynurenine/indole and serotonin pathways of tryptophan metabolism in ovarian cancer

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.isci.2024.111488
  
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sciencedirect.com/science/article/pii/S2589004224027159
Mar 2025
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A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.03.007
  
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sciencedirect.com/science/article/pii/S1535610825001084
Feb 2025
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The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8+ T cells in mice

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1. scibot 20 Feb 2025
  
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  DOI: 10.1128/msystems.01567-24
  
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sciencedirect.com/org/science/article/pii/S2379507725000066
Jan 2025
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101887
  
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sciencedirect.com/science/article/pii/S266637912400658X
Sep 2024
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101718
  
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sciencedirect.com/science/article/pii/S2666379124004397
Aug 2024
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.010
  
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sciencedirect.com/science/article/pii/S1074761324003595
Jul 2024
52.53.155.43 52.53.155.43

Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

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1. scibot 25 Jul 2024
  
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  AB_398528
  
  DOI: 10.1016/j.isci.2024.110547
  
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52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury

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1. scibot 07 Jul 2024
  
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  DOI: 10.1186/s13071-024-06349-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11221008/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Impaired autophagy in myeloid cells aggravates psoriasis-like skin inflammation through the IL-1β/CXCL2/neutrophil axis

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1. scibot 09 May 2024
  
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  DOI: 10.1186/s13578-024-01238-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11069248/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

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1. scibot 01 May 2024
  
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  BD BioscienceCat#553051; RRID: AB_393575
  
  DOI: 10.1016/j.celrep.2024.113942
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection

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1. scibot 31 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107552
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10460994/
52.53.155.43 52.53.155.43

IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107531
  
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52.53.155.43/177943f7d2a1e7d0acb51004d129b2330d72300b/PIIS2589004223016085-html.html
May 2023
www.cell.com www.cell.com

Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer

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1. scibot 03 May 2023
  
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  DOI: 10.1016/j.chom.2023.04.010
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(23)00161-0
Apr 2023
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SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.02.004
  
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sciencedirect.com/science/article/pii/S1097276523000837
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A neutrophil response linked to tumor control in immunotherapy

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1. scibot 04 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.02.032
  
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sciencedirect.com/science/article/pii/S0092867423002106
Jan 2023
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CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111874
  
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sciencedirect.com/science/article/pii/S2211124722017703
Sep 2022
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Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome

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1. scibot 10 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111314
  
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sciencedirect.com/science/article/pii/S221112472201138X
Aug 2022
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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

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1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111205
  
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sciencedirect.com/science/article/pii/S2211124722010221
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Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111150
  
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sciencedirect.com/science/article/pii/S2211124722009597
Jun 2022
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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

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  DOI: 10.1016/j.cell.2022.04.039
  
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sciencedirect.com/science/article/pii/S0092867422005372
May 2022
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STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

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1. scibot 26 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110838
  
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sciencedirect.com/science/article/pii/S2211124722006118
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer

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1. scibot 15 Mar 2022
  
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  DOI: 10.1126/sciadv.abk3338
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8865802/
Feb 2022
www.nature.com www.nature.com

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

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1. scibot 05 Feb 2022
  
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  DOI: 10.1038/s41467-022-28172-4
  
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nature.com/articles/s41467-022-28172-4
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Epithelial colonization by gut dendritic cells promotes their functional diversification

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1. scibot 15 Dec 2021
  
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  DOI: 10.1016/j.immuni.2021.11.008
  
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sciencedirect.com/science/article/pii/S1074761321004994
Nov 2021
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Isolation and enrichment of mouse splenic T cells for ex vivo and in vivo T cell receptor stimulation assays

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1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.xpro.2021.100961
  
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sciencedirect.com/science/article/pii/S2666166721006675
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

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1. scibot 15 Nov 2021
  
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  DOI: 10.7554/eLife.61999
  
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Oct 2021
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Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity

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Jul 2021
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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia

2
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  DOI: 10.1016/j.ccell.2017.10.004
  
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MYC deficiency impairs the development of effector/memory T lymphocytes

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Jun 2021
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A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis

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May 2021
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Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

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Feb 2021
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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

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Jan 2021
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Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection

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SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity

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Nov 2020
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Localized hydrogel delivery of dendritic cells for attenuation of multiple sclerosis in a murine model

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Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells

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Sep 2020
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Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

1
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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

2
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  RRID:AB_398528
  
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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

1
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Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity

1
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cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia

1
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  DOI: 10.1158/2159-8290.CD-19-0471
  
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Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes

1
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sciencedirect.com/science/article/pii/S221112472030855X
Jan 2020
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B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis

1
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Brief exposure to hyperglycemia activates dendritic cells in vitro and in vivo

1
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  DOI: 10.1002/jcp.29380
  
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Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

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Untitled document

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  DOI: 10.1016/j.stem.2018.12.003
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.020
  
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Untitled document

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  DOI: 10.1111/bph.14667
  
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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells

1
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  DOI: 10.1016/j.celrep.2019.03.004
  
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Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

1
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Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

1
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A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia

1
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europepmc.org/articles/PMC5691892/
Nov 2017
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Cytokine profile of NALT during acute stress and its possible effect on IgA secretion

1
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Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke

1
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  AB_398528
  
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jneurosci.org/content/35/20/7777.long
Dec 2015
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Untitled document

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  AB_398528
  
  Antibody ID: AB_398528
  Target Antigen: CD4 See NCBI gene
  Vendor: BD Biosciences
  Cat Num: 553051
  Proper Citation: (BD Biosciences Cat# 553051, RRID:AB_398528)
  Reference:
  Clonality: monoclonal antibody
  Clone ID: RM4-5
  Host Organism: rat
  Comments: manufacturer recommendations: Flow Cytometry; FCM mouse
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