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  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A functional connection between the Microprocessor and a variant NEXT complex
    1
    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.015

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    sciencedirect.com/science/article/pii/S1097276524008554
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.chembiol.2024.09.004

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    sciencedirect.com/science/article/pii/S2451945624003969
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 specifically regulates ISL1 during embryonic urinary tract formation
    1
    1. scibot 05 Oct 2024
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      DOI: 10.1038/s41598-024-74303-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11447050/
  6. www.sciencedirect.com www.sciencedirect.com
    Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1016/j.cmet.2024.09.002

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    sciencedirect.com/science/article/pii/S1550413124003668
  7. aacrjournals.org aacrjournals.org
    Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1158/1541-7786.MCR-20-0115

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    aacrjournals.org/mcr/article/19/1/61/271645/Metformin-Mitigates-DPP-4-Inhibitor-Induced-Breast
  8. Sep 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tanomastat exerts multi-targeted inhibitory effects on viral capsid dissociation and RNA replication in human enteroviruses
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.ebiom.2024.105277

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    ncbi.nlm.nih.gov/pmc/articles/PMC11419895/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
    1
    1. scibot 26 Sep 2024
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      DOI: 10.7554/eLife.97916

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    ncbi.nlm.nih.gov/pmc/articles/PMC11415076/
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    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724011136
  12. www.sciencedirect.com www.sciencedirect.com
    Generation of Rybp Homozygous Knockout murine ES cell line GIBHe001-A-1 by using CRISPR/Cas9 technology
    1
    1. scibot 25 Sep 2024
      RRID:AB_476730

      DOI: 10.1016/j.scr.2019.101638

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    sciencedirect.com/science/article/pii/S1873506119302685
  13. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  14. www.sciencedirect.com www.sciencedirect.com
    Key roles of C2/GAP domains in SYNGAP1-related pathophysiology
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114733

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    sciencedirect.com/science/article/pii/S2211124724010842
  15. Aug 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114598

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    sciencedirect.com/science/article/pii/S2211124724009379
  17. www.sciencedirect.com www.sciencedirect.com
    Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114616

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    sciencedirect.com/science/article/pii/S2211124724009665
  18. academic.oup.com academic.oup.com
    Loss of Fbxw7 in Sertoli cells impairs testis development and causes infertility in mice
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1093/biolre/ioz230

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    academic.oup.com/biolreprod/biolreprod/advance-article-abstract/doi/10.1093/biolre/ioz230/5688712
  19. www.embopress.org www.embopress.org
    HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis
    1
    1. scibot 02 Aug 2024
      A2228

      DOI: 10.15252/embr.202153391

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    embopress.org/doi/full/10.15252/embr.202153391
  20. www.tandfonline.com www.tandfonline.com
    M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1080/15548627.2021.1938912

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    tandfonline.com/doi/full/10.1080/15548627.2021.1938912
  21. www.ahajournals.org www.ahajournals.org
    Sphingomyelin Synthase 2 Inhibition Ameliorates Cerebral Ischemic Reperfusion Injury Through Reducing the Recruitment of Toll‐Like Receptor 4 to Lipid Rafts
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1161/JAHA.119.012885

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    ahajournals.org/doi/abs/10.1161/JAHA.119.012885
  22. search.proquest.com search.proquest.com
    Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes - ProQuest
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1371/journal.pone.0186707.t001

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    search.proquest.com/docview/1952658506
  23. Jul 2024
  24. www.cell.com www.cell.com
    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
    1
    1. scibot 25 Jul 2024
      RRID:AB_476697

      DOI: 10.1016/j.chembiol.2024.06.012

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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
    1
    1. scibot 17 Jul 2024
      RRID:AB_476697

      DOI: 10.1016/j.xcrm.2024.101653

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293357/
  26. www.sciencedirect.com www.sciencedirect.com
    Competition between two HUSH complexes orchestrates the immune response to retroelement invasion
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.molcel.2024.06.020

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    sciencedirect.com/science/article/pii/S1097276524005276
  27. Jun 2024
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Jun 2024
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      DOI: 10.1111/bph.16441

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16441
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
    1
    1. scibot 27 Jun 2024
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      DOI: 10.7554/eLife.85560

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    ncbi.nlm.nih.gov/pmc/articles/PMC11189632/
  30. www.sciencedirect.com www.sciencedirect.com
    Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1016/j.devcel.2024.05.008

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    sciencedirect.com/science/article/pii/S1534580724003253
  31. May 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females
    1
    1. scibot 30 May 2024
      RRID: AB_476697

      DOI: 10.1016/j.celrep.2024.114293

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    sciencedirect.com/science/article/pii/S2211124724006211
  33. www.sciencedirect.com www.sciencedirect.com
    Analyzing efficiency of a lentiviral shRNA knockdown system in human enteroids using western blot and flow cytometry
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.xpro.2024.103082

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    sciencedirect.com/science/article/pii/S2666166724002478
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis
    1
    1. scibot 30 May 2024
      RRID:AB_476697

      DOI: 10.3389/fnsyn.2024.1384625

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    ncbi.nlm.nih.gov/pmc/articles/PMC11116793/
  35. www.sciencedirect.com www.sciencedirect.com
    Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.stem.2024.04.022

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    sciencedirect.com/science/article/pii/S1934590924001772
  36. www.sciencedirect.com www.sciencedirect.com
    Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly
    1
    1. scibot 16 May 2024
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      DOI: 10.1016/j.str.2024.04.016

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    sciencedirect.com/science/article/pii/S0969212624001424
  37. 52.53.155.43 52.53.155.43
    Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
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      DOI: 10.1101/2024.02.22.581558

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    52.53.155.43/8391d5e75ba57c9ef8c1ebe0973fe3c1602760fc/2024.02.22.581558v3.full-html.html
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
    1
    1. scibot 15 May 2024
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      DOI: 10.1084/jem.20221122

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    ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
  39. www.sciencedirect.com www.sciencedirect.com
    Central carbon metabolism exhibits unique characteristics during the handling of fungal patterns by monocyte-derived dendritic cells
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      DOI: 10.1016/j.redox.2024.103187

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    sciencedirect.com/science/article/pii/S2213231724001654
  40. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.celrep.2024.114211

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    sciencedirect.com/science/article/pii/S2211124724005394
  41. 52.53.155.43 52.53.155.43
    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
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      DOI: 10.1016/j.celrep.2024.114173

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      DOI: 10.1016/j.celrep.2024.114173

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    52.53.155.43/7165d3b920717872e9ecee45ef5f3cb3a7917c57/mmc6-html.html
  42. Apr 2024
  43. www.embopress.org www.embopress.org
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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      DOI: 10.1038/s44318-024-00065-w

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      DOI: 10.1038/s44318-024-00065-w

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    embopress.org/doi/10.1038/s44318-024-00065-w
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Standardized In Vitro Models of Human Adipose Tissue Reveal Metabolic Flexibility in Brown Adipocyte Thermogenesis
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1210/endocr/bqad161

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    ncbi.nlm.nih.gov/pmc/articles/PMC11032247/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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      DOI: 10.1038/s44318-024-00065-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  46. 52.53.155.43 52.53.155.43
    gaae015-html.html
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    1. scibot 19 Apr 2024
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      DOI: 10.1093/molehr/gaae015

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    52.53.155.43/2937ae15ffb949fde49a3f9100cc82616d52fb7b/gaae015-html.html
  47. www.sciencedirect.com www.sciencedirect.com
    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
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      AB_476697

      DOI: 10.1016/j.immuni.2024.03.020

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    Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties
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    Chromatin context-dependent regulation and epigenetic manipulation of prime editing
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    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
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    Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress
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    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
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    Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer
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    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
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    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
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  59. Jan 2024
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    Toll-mediated airway homeostasis is essential for fly survival upon injection of RasV12-GFP oncogenic cells
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    Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development
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    Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    Loss of Depalmitoylation Disrupts Homeostatic Plasticity of AMPARs in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis
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    BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation
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  66. Dec 2023
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    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
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    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
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    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
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    The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency
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  73. Nov 2023
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    Mitochondrial Permeability Transition Regulator, Cyclophilin D, is Transcriptionally Activated by C/EBP During Adipogenesis
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    Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis
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    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
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    LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol remodeling with mitochondrial transport
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    In vitro generation of mouse morula-like cells
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    Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways
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    Mouse models of human CNTNAP1-associated congenital hypomyelinating neuropathy and genetic restoration of murine neurological deficits
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    Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses
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    Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a male mouse model of head-and-neck cancer
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    Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia
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  86. Sep 2023
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
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    The C2 domain of calpain 5 contributes to enzyme activation and membrane localization
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    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
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    EZH2 specifically regulates ISL1 during embryonic urinary tract formation
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    ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer
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  95. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
    1
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  97. www.nature.com www.nature.com
    Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
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  98. Jul 2023
  99. 52.53.155.43 52.53.155.43
    HIV-1 Tat Upregulates TREM1 Expression in Human Microglia
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      DOI: 10.4049/jimmunol.2300152

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  100. www.sciencedirect.com www.sciencedirect.com
    Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity
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      DOI: 10.7554/eLife.84570

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  102. Jun 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tubular IL-1β Induces Salt Sensitivity in Diabetes by Activating Renal Macrophages
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      DOI: 10.1161/CIRCRESAHA.121.320239

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex specific molecular networks and key drivers of Alzheimer’s disease
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  105. www.nature.com www.nature.com
    Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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      DOI: 10.1038/s41596-023-00831-w

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  106. www.sciencedirect.com www.sciencedirect.com
    ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts
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  107. www.microbiologyresearch.org www.microbiologyresearch.org
    IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia
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  108. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
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    embopress.org/doi/10.15252/embr.202256430
  109. aacrjournals.org aacrjournals.org
    TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
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      DOI: 10.1158/0008-5472.CAN-22-3133

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    aacrjournals.org/cancerres/article/83/7/997/718999/TLE3-Sustains-Luminal-Breast-Cancer-Lineage
  110. www.sciencedirect.com www.sciencedirect.com
    Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
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  111. May 2023
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    Disruption of CDK7 signaling leads to catastrophic chromosomal instability coupled with a loss of condensin-mediated chromatin compaction
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  113. www.sciencedirect.com www.sciencedirect.com
    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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  114. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  115. Apr 2023
  116. www.sciencedirect.com www.sciencedirect.com
    Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
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      DOI: 10.1016/j.xcrm.2023.101024

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  117. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer
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  118. link.springer.com link.springer.com
    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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      DOI: 10.1186/s12935-023-02884-z

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  119. link.springer.com link.springer.com
    The activation of mGluR4 rescues parallel fiber synaptic transmission and LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
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      DOI: 10.1186/s13229-023-00547-4

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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
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  121. www.sciencedirect.com www.sciencedirect.com
    Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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  123. Mar 2023
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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      DOI: 10.1158/2767-9764.CRC-22-0208

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
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      DOI: 10.1158/2767-9764.CRC-22-0119

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
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  127. 52.53.155.43 52.53.155.43
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
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  129. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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  130. Feb 2023
  131. link.springer.com link.springer.com
    Axotomy results in an increase in Thy-1 protein in the 35-day-old rat supraoptic nucleus
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      DOI: 10.1007/s00221-023-06562-4

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  132. Jan 2023
  133. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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  134. www.frontiersin.org www.frontiersin.org
    A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
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      DOI: 10.3389/fimmu.2022.1083119

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism
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  136. www.biorxiv.org www.biorxiv.org
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
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  137. www.cell.com www.cell.com
    Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation
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  138. www.sciencedirect.com www.sciencedirect.com
    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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  139. Dec 2022
  140. www.mdpi.com www.mdpi.com
    CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca2+ via Mitochondrial NCLX
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  141. www.karger.com www.karger.com
    Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA
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    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
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    EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression
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  145. Nov 2022
  146. www.sciencedirect.com www.sciencedirect.com
    Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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      DOI: 10.1080/15548627.2021.1999561

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  148. academic.oup.com academic.oup.com
    Estrogen Receptor Beta 1: A Potential Therapeutic Target for Female Triple Negative Breast Cancer
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      DOI: 10.1210/endocr/bqac172

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    Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis
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  150. Oct 2022
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Global Protein-RNA Interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
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  152. www.sciencedirect.com www.sciencedirect.com
    Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology
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  153. Sep 2022
  154. www.sciencedirect.com www.sciencedirect.com
    Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    Heme oxygenase-1 mitigates liver injury and fibrosis via modulation of LNX1/Notch1 pathway in myeloid cells
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  157. Aug 2022
  158. 52.53.155.43 52.53.155.43
    ccr-21-3603-html.html
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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    Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
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    CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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  165. Jul 2022
  166. www.nature.com www.nature.com
    Dysbindin-1A modulation of astrocytic dopamine and basal ganglia dependent behaviors relevant to schizophrenia
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurogranin, encoded by the schizophrenia risk gene NRGN, bidirectionally modulates synaptic plasticity via calmodulin-dependent regulation of the neuronal phosphoproteome
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  168. academic.oup.com academic.oup.com
    Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function
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  169. Jun 2022
  170. www.nature.com www.nature.com
    MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
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    C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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    TRPV6 channel mediates alcohol-induced gut barrier dysfunction and systemic response
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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  176. May 2022
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    Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model
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  178. elifesciences.org elifesciences.org
    Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enterocyte HKDC1 Modulates Intestinal Glucose Absorption in Male Mice Fed a High-Fat Diet
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  180. Apr 2022
  181. www.sciencedirect.com www.sciencedirect.com
    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blood-brain barrier permeability is regulated by lipid transport-dependent suppression of caveolae-mediated transcytosis
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      DOI: 10.1016/j.neuron.2017.03.043

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  184. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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  185. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LRRK2-G2019S mice display alterations in glutamatergic synaptic transmission in midbrain dopamine neurons
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers
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  187. Mar 2022
  188. www.sciencedirect.com www.sciencedirect.com
    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
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    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
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    Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy
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      DOI: 10.1016/j.neuron.2022.01.035

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  192. www.sciencedirect.com www.sciencedirect.com
    Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis
    1
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      DOI: 10.1016/j.ebiom.2022.103891

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  193. Feb 2022
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High Iron and Iron Household Protein Contents in Perineuronal Net-Ensheathed Neurons Ensure Energy Metabolism with Safe Iron Handling
    1
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      RRID:AB_476697

      DOI: 10.3390/ijms23031634

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  195. elifesciences.org elifesciences.org
    Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae
    1
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      DOI: 10.7554/eLife.73439

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  196. www.sciencedirect.com www.sciencedirect.com
    Dopamine signaling in the dorsomedial striatum promotes compulsive behavior
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      DOI: 10.1016/j.cub.2022.01.055

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    sciencedirect.com/science/article/pii/S0960982222001178
  197. www.sciencedirect.com www.sciencedirect.com
    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function
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  199. www.sciencedirect.com www.sciencedirect.com
    An oncogenic enhancer encodes selective selenium dependency in AML
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  200. Jan 2022
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    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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      RRID:AB_476697

      DOI: 10.1016/j.devcel.2021.12.020

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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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      DOI: 10.1016/j.immuni.2021.12.002

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  203. Dec 2021
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    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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  205. www.sciencedirect.com www.sciencedirect.com
    Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
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  207. www.sciencedirect.com www.sciencedirect.com
    Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity
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    Sarm1 haploinsufficiency or low expression levels after antisense oligonucleotides delay programmed axon degeneration
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    Terahertz exposure enhances neuronal synaptic transmission and oligodendrocyte differentiation in vitro
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    A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function
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      DOI: 10.1126/sciadv.abf6935

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    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S1550413121005398
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    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
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  213. Nov 2021
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    Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
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    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
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      DOI: 10.3389/fcell.2021.738731

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    A high-throughput protocol for monitoring starvation-induced autophagy in real time in mouse embryonic fibroblasts
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      DOI: 10.1016/j.xpro.2021.100966

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    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
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    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
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  220. Oct 2021
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    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
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  222. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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    Differences in Glycolysis and Mitochondrial Respiration between Cytotrophoblast and Syncytiotrophoblast In-Vitro: Evidence for Sexual Dimorphism
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      DOI: 10.3390/ijms221910875

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    A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells
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    The Role of the Carnitine/Organic Cation Transporter Novel 2 in the Clinical Outcome of Patients With Locally Advanced Esophageal Carcinoma Treated With Oxaliplatin
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      DOI: 10.3389/fphar.2021.684545

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  227. academic.oup.com academic.oup.com
    Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity
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      DOI: 10.1210/clinem/dgab680

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab680/6370132
  228. Sep 2021
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    ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions
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      DOI: 10.1016/j.omtn.2021.07.022

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  230. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effect of modulating glutamate signaling on myelinating oligodendrocytes and their development—A study in the zebrafish model
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      DOI: 10.1002/jnr.24940

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    ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction
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    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
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      DOI: 10.7150/thno.59728

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