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    IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis
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    Generation of Rybp Homozygous Knockout murine ES cell line GIBHe001-A-1 by using CRISPR/Cas9 technology
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  4. Jun 2024
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    De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166698/
  6. May 2024
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    Epithelial-to-mesenchymal transition and NF-kB pathways are promoted by a mutant form of DDB2, unable to bind PCNA, in UV-damaged human cells
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  8. Mar 2024
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    Engineered FSHD mutations results in D4Z4 heterochromatin disruption and feedforward DUX4 network activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951985/
  10. Nov 2023
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    Molecular symmetry breaking in the Frizzled-dependent planar polarity pathway
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  12. Aug 2023
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    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
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  14. Jul 2023
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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  16. Jun 2023
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities
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    aacrjournals.org/cancerres/article/83/6/890/718574/Olig1-2-Expressing-Intermediate-Lineage
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    Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis
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  20. Mar 2023
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    The intramembrane COOH-terminal domain of PRRT2 regulates voltage-dependent Na+ channels
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    Neuron-restrictive silencer factor/repressor element 1-silencing transcription factor (NRSF/REST) controls spatial K+ buffering in primary cortical astrocytes
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  23. Jan 2023
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    PPARγ and C/EBPα response to acute cold stress in brown adipose tissue
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  25. Dec 2022
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    sciencedirect.com/science/article/pii/S2211124722015248
  27. Oct 2022
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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  29. Mar 2022
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    Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases
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    Pathway-specific effects of ADSL deficiency on neurodevelopment
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  32. Feb 2022
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    Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions
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  34. Jan 2022
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    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8764631/
  36. Nov 2021
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    mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion
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    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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  39. Oct 2021
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    Protein Kinase D promotes activity-dependent AMPA receptor endocytosis in hippocampal neurons
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  41. Aug 2021
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    Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue
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  48. Jul 2021
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    ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function
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    An Autonomous Oscillation Times and Executes Centriole Biogenesis
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  52. Jun 2021
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    PRRT2 modulates presynaptic Ca2+ influx by interacting with P/Q-type channels
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    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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    Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties
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    nature.com/articles/s41419-021-03828-z
  56. May 2021
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    Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors
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    cancerres.aacrjournals.org/content/81/9/2481
  58. Apr 2021
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    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
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    sciencedirect.com/science/article/pii/S0092867421003792
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  62. Dec 2020
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation
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      DOI: 10.7554/eLife.63603

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  64. Sep 2020
  65. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF
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    Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models
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    Insulin deficiency, but not resistance, exaggerates cognitive deficits in transgenic mice expressing human amyloid and tau proteins. Reversal by Exendin‐4 treatment
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    Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition
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  70. Jan 2020
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    Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex
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    Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation
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    Oxidative stress differentially induces tau dissociation from neuronal microtubules in neurites of neurons cultured from different regions of the embryonic Gallus domesticus brain
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    LRRK2 phosphorylation on synapsin I regulates glutamate release at presynaptic sites
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy
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    Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
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    The Long Non-Coding RNA lep-5 Promotes the Juvenile-to-Adult Transition by Destabilizing LIN-28
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  82. Nov 2018
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    Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
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    A damaged DNA binding protein 2 mutation disrupting interaction with proliferating-cell nuclear antigen affects DNA repair and confers proliferation advantage
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    TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer
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  87. Nov 2017
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    A Dual Function for Prickle in Regulating Frizzled Stability during Feedback-Dependent Amplification of Planar Polarity
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
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    KChIP2 is a core transcriptional regulator of cardiac excitability
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    Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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    Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses
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