Hypothesis

262 Matching Annotations

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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

1
1. scibot 03 Sep 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.immuni.2025.07.024
  
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sciencedirect.com/science/article/pii/S1074761325003334
Aug 2025
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MAVS phosphorylation acts as a cellular stress sensor that modulates antiviral immunity

1
1. scibot 15 Aug 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.isci.2025.113256
  
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sciencedirect.com/science/article/pii/S2589004225015172
Jun 2025
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Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform

1
1. scibot 21 Jun 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.xcrm.2025.102198
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
May 2025
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GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration

1
1. scibot 29 May 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.neuron.2025.04.033
  
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sciencedirect.com/science/article/pii/S0896627325003459
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PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation

1
1. scibot 22 May 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115735
  
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sciencedirect.com/science/article/pii/S2211124725005066
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A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection

1
1. scibot 19 May 2025
  
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  RRID:AB_823547
  
  DOI: 10.1038/s44318-025-00412-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048508/
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SIRT2 suppresses aging-associated cGAS activation and protects aged mice from severe COVID-19

1
1. scibot 17 May 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115562
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074670/
Apr 2025
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SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases

1
1. scibot 24 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115588
  
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sciencedirect.com/science/article/pii/S2211124725003596
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Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity

1
1. scibot 19 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115572
  
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sciencedirect.com/science/article/pii/S2211124725003432
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Herpes simplex virus 1 encodes a STING antagonist that can be therapeutically targeted

1
1. scibot 17 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.xcrm.2025.102051
  
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sciencedirect.com/science/article/pii/S2666379125001247
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

1
1. scibot 09 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.immuni.2025.03.005
  
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sciencedirect.com/science/article/pii/S1074761325001244
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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

1
1. scibot 05 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.molcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1097276525002011
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BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity

1
1. scibot 03 Apr 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115493
  
  Resource: (Cell Signaling Technology Cat# 4947, RRID:AB_823547)
  
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sciencedirect.com/science/article/pii/S2211124725002645
Mar 2025
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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity

1
1. scibot 06 Mar 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2025.115397
  
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sciencedirect.com/science/article/pii/S2211124725001688
Feb 2025
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RBM43 controls PGC1α translation and a PGC1α-STING signaling axis

1
1. scibot 20 Feb 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.cmet.2025.01.013
  
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sciencedirect.com/science/article/pii/S1550413125000130
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

1
1. scibot 13 Feb 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.cell.2025.01.027
  
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sciencedirect.com/science/article/pii/S0092867425000960
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

7
1. scibot 07 Feb 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2024.114960
  
  Resource: (Cell Signaling Technology Cat# 4947, RRID:AB_823547)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_823547
  
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2. scibot 06 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
3. scibot 05 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
4. scibot 04 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
5. scibot 03 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
6. scibot 02 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
7. scibot 01 Feb 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
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An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment

1
1. scibot 04 Feb 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.chembiol.2025.01.004
  
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sciencedirect.com/science/article/pii/S2451945625000042
Jan 2025
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

31
1. scibot 31 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
2. scibot 30 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
3. scibot 29 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
4. scibot 28 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
5. scibot 27 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
6. scibot 26 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
7. scibot 25 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
8. scibot 24 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
9. scibot 23 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
10. scibot 22 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
11. scibot 21 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
12. scibot 20 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
13. scibot 19 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
14. scibot 18 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
15. scibot 17 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
16. scibot 16 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
17. scibot 15 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
18. scibot 14 Jan 2025
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
19. scibot 13 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
20. scibot 12 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
21. scibot 11 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
22. scibot 10 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
23. scibot 09 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
24. scibot 08 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
25. scibot 07 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
26. scibot 06 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
27. scibot 05 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
28. scibot 04 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
29. scibot 03 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
30. scibot 02 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
31. scibot 01 Jan 2025
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Aberrant STING activation promotes macrophage senescence by suppressing autophagy in vascular aging from diabetes

1
1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111594
  
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Anti-herpetic tau preserves neurons via the cGAS-STING-TBK1 pathway in Alzheimer’s disease

1
1. scibot 03 Jan 2025
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2024.115109
  
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

31
1. scibot 31 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
2. scibot 30 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
3. scibot 29 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
4. scibot 28 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
5. scibot 27 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
6. scibot 26 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
7. scibot 25 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
8. scibot 24 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
9. scibot 23 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
10. scibot 22 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
11. scibot 21 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
12. scibot 20 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
13. scibot 19 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
14. scibot 18 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
15. scibot 17 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
16. scibot 16 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
17. scibot 15 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
18. scibot 14 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
19. scibot 13 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
20. scibot 12 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
21. scibot 11 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
22. scibot 10 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
23. scibot 09 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
24. scibot 08 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
25. scibot 07 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
26. scibot 06 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
27. scibot 05 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
28. scibot 04 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
29. scibot 03 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
30. scibot 02 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
31. scibot 01 Dec 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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sciencedirect.com/science/article/pii/S2211124724013111
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Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3

1
1. scibot 24 Dec 2024
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.immuni.2024.11.020
  
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Pressure to evade cell-autonomous innate sensing reveals interplay between mitophagy, IFN signaling, and SARS-CoV-2 evolution

1
1. scibot 21 Dec 2024
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.celrep.2024.115115
  
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MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling

1
1. scibot 18 Dec 2024
  
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  RRID:AB_823547
  
  DOI: 10.1016/j.molcel.2024.11.026
  
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The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

1
1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.017
  
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TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

2
1. scibot 29 Nov 2024
  
  in Public
  
  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_823547
2. scibot 28 Nov 2024
  
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  RRID:AB_823547
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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Type I IFN drives unconventional IL-1β secretion in lupus monocytes

1
1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.immuni.2024.09.004
  
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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer

1
1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.09.024
  
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Sep 2024
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IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1

1
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  DOI: 10.1016/j.isci.2024.110693
  
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NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.chom.2019.02.013
  
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InsP 3 R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca 2+ elevation and TBK1 activity

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E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS

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The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response

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SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways

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A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1

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PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection

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pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism

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Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver

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RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release

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Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response

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Development of nitroalkene-based inhibitors to target STING-dependent inflammation

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Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

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Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination

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ISGylation by HERCs facilitates STING activation

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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

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HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus

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HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

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Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production

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RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion

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Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

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Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro

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Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation

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Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity

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Different modulation of STING/TBK1/IRF3 signaling by advanced glycation end products

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Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy

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Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children

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Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

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SARS-CoV-2 Nsp15 suppresses type I interferon production by inhibiting IRF3 phosphorylation and nuclear translocation

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4-Octyl itaconate restricts STING activation by blocking its palmitoylation

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Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

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Jun 2023
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Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response

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A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

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The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB

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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome

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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway

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C9ORF72 suppresses JAK-STAT mediated inflammation

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Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

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Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

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Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

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Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity

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ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING

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NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking

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Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS

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Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response

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The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER

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Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling

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Cancer cell-derived type I interferons instruct tumor monocyte polarization

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Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response

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Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages

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AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity

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Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade

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Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD36

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Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis

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Ku proteins promote DNA binding and condensation of cyclic GMP-AMP synthase

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The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways

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The redox cycling of STAT2 maintains innate immune homeostasis

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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

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Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

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Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation

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The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity

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cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model

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ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

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The SETDB1–TRIM28 complex suppresses antitumor immunity

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LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity

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DDX41 is required for cGAS-STING activation against DNA virus infection

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Protocol to induce and assess cGAS-STING pathway activation in vitro

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Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

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The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62

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The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis

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Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

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Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site

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PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade

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K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy

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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

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IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

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Differential effects of viral nucleic acid sensor signaling pathways on testicular Sertoli and Leydig cells

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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

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The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation

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A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP

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Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

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FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C

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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

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NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation

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Translation stress and collided ribosomes are co-activators of cGAS

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Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

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