116 Matching Annotations
  1. Aug 2025
  2. www.biorxiv.org www.biorxiv.org
    MATCAP1 preferentially binds an expanded tubulin conformation to generate detyrosinated and ΔC2 α-tubulin
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    biorxiv.org/content/10.1101/2025.08.14.670257v1
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNF20-mediated H2B monoubiquitination protects stalled forks from degradation and promotes fork restart
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12331980/
  4. www.biorxiv.org www.biorxiv.org
    Using CCDC6 immunostaining in conjunction with the RAD51 HRD assay as a novel approach to expand PARPi treatment eligibility in HGSOC patients
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    biorxiv.org/content/10.1101/2025.07.29.667411v1
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12276220/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments
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    pmc.ncbi.nlm.nih.gov/articles/PMC12237251/
  8. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013793-main-html.html
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    52.53.155.43/72514dc41d46f248426b083113977801d68ad9dc/1-s2.0-S2589004225013793-main-html.html
  9. www.mdpi.com www.mdpi.com
    Cellular Lyso-Gb3 Is a Biomarker for Mucolipidosis II
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    mdpi.com/1422-0067/26/13/6275
  10. Jun 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Automated Imaging Method for Quantification of Changes to the Endomembrane System in Mammalian Spheroid Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152110/
  12. May 2025
  13. www.sciencedirect.com www.sciencedirect.com
    Development and validation of the Azu-Eos as a fluorescence-free staining method for enhanced bright-field microscopy in the comet assay
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    sciencedirect.com/science/article/pii/S104620232500132X
  14. www.sciencedirect.com www.sciencedirect.com
    Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
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    sciencedirect.com/science/article/pii/S0092867425005094
  15. Apr 2025
  16. www.nature.com www.nature.com
    Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling
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    nature.com/articles/s41594-025-01522-8
  17. www.nature.com www.nature.com
    Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics
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    nature.com/articles/s41556-025-01637-6
  18. Mar 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes
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    sciencedirect.com/science/article/pii/S0092867425002557
  20. Feb 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends
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    pmc.ncbi.nlm.nih.gov/articles/PMC11812572/
  22. Jan 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In and out of Replication Stress: PCNA/RPA1-Based Dynamics of Fork Stalling and Restart in the Same Cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC11765805/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantitative imaging of loop extruders rebuilding interphase genome architecture after mitosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11716112/
  25. Dec 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZBTB48 is a priming factor regulating B-cell-specific CIITA expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11649694/
  27. www.sciencedirect.com www.sciencedirect.com
    Development of fluorescence lifetime biosensors for ATP, cAMP, citrate, and glucose using the mTurquoise2-based platform
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    sciencedirect.com/science/article/pii/S2667237524002923
  28. Nov 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An automated high-content screening and assay platform for the analysis of spheroids at subcellular resolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC11556727/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535040/
  31. Oct 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Pervasive mislocalization of pathogenic coding variants underlying human disorders
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    sciencedirect.com/science/article/pii/S0092867424010213
  33. Sep 2024
  34. www.nature.com www.nature.com
    Rapid generation of homozygous fluorescent knock-in human cells using CRISPR–Cas9 genome editing and validation by automated imaging and digital PCR screening
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    nature.com/articles/s41596-024-01043-6
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probing Gag-Env dynamics at HIV-1 assembly sites using live-cell microscopy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11406925/
  36. www.sciencedirect.com www.sciencedirect.com
    Differential Requirements for Centrioles in Mitotic Centrosome Growth and Maintenance
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    sciencedirect.com/science/article/pii/S1534580719305222
  37. Aug 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335259/
  39. www.sciencedirect.com www.sciencedirect.com
    RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes
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    sciencedirect.com/science/article/pii/S2211124724009239
  40. bmcbioinformatics.biomedcentral.com bmcbioinformatics.biomedcentral.com
    A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells
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    bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-021-04334-x
  41. www.mdpi.com www.mdpi.com
    Dynamics of Replication-Associated Protein Levels through the Cell Cycle
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    mdpi.com/1422-0067/25/15/8230
  42. Jul 2024
  43. www.sciencedirect.com www.sciencedirect.com
    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    sciencedirect.com/science/article/pii/S2211124724007460
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The endoplasmic reticulum connects to the nucleus by constricted junctions that mature after mitosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11239909/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fluorescence lifetime multiplexing with fluorogen activating protein FAST variants
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219735/
  46. May 2024
  47. www.sciencedirect.com www.sciencedirect.com
    A unified mechanism for PARP inhibitor-induced PARP1 chromatin retention at DNA damage sites in living cells
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    sciencedirect.com/science/article/pii/S221112472400562X
  48. Mar 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabinoid Receptor Signaling is Dependent on Sub-Cellular Location
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983902/
  50. www.sciencedirect.com www.sciencedirect.com
    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    sciencedirect.com/science/article/pii/S1097276524001722
  51. Feb 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849593/
  53. www.biorxiv.org www.biorxiv.org
    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications
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    biorxiv.org/content/10.1101/2023.12.16.571619v1
  54. www.sciencedirect.com www.sciencedirect.com
    Zn2+-dependent functional switching of ERp18, an ER-resident thioredoxin-like protein
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    sciencedirect.com/science/article/pii/S221112472400010X
  55. Jan 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Excessive reactive oxygen species induce transcription-dependent replication stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10063555/
  57. link.springer.com link.springer.com
    HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor
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    link.springer.com/article/10.1038/s41586-023-06966-w
  58. Dec 2023
  59. www.sciencedirect.com www.sciencedirect.com
    u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions
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    sciencedirect.com/science/article/pii/S2667237523003260
  60. www.mdpi.com www.mdpi.com
    CellTool: An Open-Source Software Combining Bio-Image Analysis and Mathematical Modeling for the Study of DNA Repair Dynamics
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    mdpi.com/1422-0067/24/23/16784
  61. Oct 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serial-section Electron Tomography and Quantitative Analysis of Microtubule Organization in 3D-reconstructed Mitotic Spindles
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    ncbi.nlm.nih.gov/pmc/articles/PMC10603263/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Removal of hypersignaling endosomes by simaphagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11062362/
  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER
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    sciencedirect.com/science/article/pii/S2211124723007532
  66. Jun 2023
  67. www.sciencedirect.com www.sciencedirect.com
    ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts
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    sciencedirect.com/science/article/pii/S1097276523003842
  68. www.nature.com www.nature.com
    A general method for the development of multicolor biosensors with large dynamic ranges
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    nature.com/articles/s41589-023-01350-1
  69. www.embopress.org www.embopress.org
    STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory
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    embopress.org/doi/10.15252/embj.2022112259
  70. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Cationic Solution and Solid-State Emitters – Robust Imaging Agents for Cells, Bacteria, and Protists
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202300334
  71. May 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Dynamics of cell rounding during detachment
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    sciencedirect.com/science/article/pii/S2589004223007733
  73. Apr 2023
  74. www.nature.com www.nature.com
    CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion
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    nature.com/articles/s41586-023-05961-5
  75. www.sciencedirect.com www.sciencedirect.com
    Monitoring and assessment of lysosomal membrane damage in cultured cells using the high-content imager
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    sciencedirect.com/science/article/pii/S2666166723001946
  76. Mar 2023
  77. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276523001211
  78. www.biorxiv.org www.biorxiv.org
    The junctions connecting the endoplasmic reticulum to the nuclear envelope are constricted and remodelled during the cell cycle
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    biorxiv.org/content/10.1101/2023.01.31.526419v2
  79. Jan 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Chemogenetic emulation of intraneuronal oxidative stress affects synaptic plasticity
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    sciencedirect.com/science/article/pii/S2213231723000058
  81. www.nature.com www.nature.com
    A quantitative map of nuclear pore assembly reveals two distinct mechanisms
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    nature.com/articles/s41586-022-05528-w
  82. Dec 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An imaging-based RNA interference screen for modulators of the Rab6-mediated Golgi-to-ER pathway in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9745180/
  84. www.nature.com www.nature.com
    Protein-Peptide Turnover Profiling reveals the order of PTM addition and removal during protein maturation
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    nature.com/articles/s41467-022-35054-2
  85. Oct 2022
  86. elifesciences.org elifesciences.org
    A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3
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    elifesciences.org/articles/81755
  87. www.nature.com www.nature.com
    HT-smFISH: a cost-effective and flexible workflow for high-throughput single-molecule RNA imaging
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    nature.com/articles/s41596-022-00750-2
  88. www.nature.com www.nature.com
    The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies
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    nature.com/articles/s41467-022-33434-2
  89. Sep 2022
  90. www.sciencedirect.com www.sciencedirect.com
    Opto-katanin, an optogenetic tool for localized, microtubule disassembly
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    sciencedirect.com/science/article/pii/S0960982222014543
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Operation of a TCA cycle subnetwork in the mammalian nucleus
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    ncbi.nlm.nih.gov/pmc/articles/PMC9432838/
  92. Aug 2022
  93. elifesciences.org elifesciences.org
    Three-dimensional structure of kinetochore-fibers in human mitotic spindles
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    elifesciences.org/articles/75459
  94. www.sciencedirect.com www.sciencedirect.com
    EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules
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    sciencedirect.com/science/article/pii/S0960982222011289
  95. Jul 2022
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9302971/
  97. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
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    sciencedirect.com/science/article/pii/S1097276522005779
  98. May 2022
  99. www.sciencedirect.com www.sciencedirect.com
    The Taspase1/Myosin1f-axis regulates filopodia dynamics
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    sciencedirect.com/science/article/pii/S2589004222006265
  100. Apr 2022
  101. www.nature.com www.nature.com
    Sister chromatid–sensitive Hi-C to map the conformation of replicated genomes
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    nature.com/articles/s41596-022-00687-6
  102. www.sciencedirect.com www.sciencedirect.com
    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
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    sciencedirect.com/science/article/pii/S1097276522002684
  103. Jan 2022
  104. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A modular platform for automated cryo-FIB workflows
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    pmc.ncbi.nlm.nih.gov/articles/PMC8769651/
  105. Dec 2021
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel live-cell imaging assay reveals regulation of endosome maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8635980/
  107. Nov 2021
  108. www.sciencedirect.com www.sciencedirect.com
    The Aurora B gradient sustains kinetochore stability in anaphase
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    sciencedirect.com/science/article/pii/S2211124721012821
  109. Sep 2021
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
  111. bmcbioinformatics.biomedcentral.com bmcbioinformatics.biomedcentral.com
    A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells
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    bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-021-04334-x
  112. Aug 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36
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    ncbi.nlm.nih.gov/pmc/articles/PMC8354635/
  114. www.nature.com www.nature.com
    A highly soluble Sleeping Beauty transposase improves control of gene insertion
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    nature.com/articles/s41587-019-0291-z
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6023461/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5495570/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5834503/
  118. www.sciencedirect.com www.sciencedirect.com
    System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection
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    sciencedirect.com/science/article/pii/S1097276519300371
  119. www.sciencedirect.com www.sciencedirect.com
    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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    sciencedirect.com/science/article/pii/S1097276519308044
  120. Jul 2021
  121. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
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    sciencedirect.com/science/article/pii/S1097276518307913
  122. Jun 2021
  123. www.tandfonline.com www.tandfonline.com
    Identification of Chemo and Radio-resistant Sub-population of Stem Cells in Human Cervical Cancer HeLa Cells
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    tandfonline.com/doi/abs/10.1080/07357907.2021.1931875
  124. www.sciencedirect.com www.sciencedirect.com
    DMA-tudor interaction modules control the specificity of in vivo condensates
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    sciencedirect.com/science/article/pii/S0092867421006255
  125. Apr 2021
  126. www.sciencedirect.com www.sciencedirect.com
    A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization
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    sciencedirect.com/science/article/pii/S0969212621001143
  127. Feb 2021
  128. www.cell.com www.cell.com
    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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    cell.com/cell-reports/abstract/S2211-1247(20)30022-X
  129. www.cell.com www.cell.com
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  130. Jan 2021
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  132. Nov 2020
  133. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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  134. Sep 2020
  135. www.sciencedirect.com www.sciencedirect.com
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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    UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
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    Molecular determinants of large cargo transport into the nucleus
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  144. Jan 2020
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    Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination
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    Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
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  150. Nov 2018
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  154. www.nature.com www.nature.com
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    Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans
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    Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings
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  161. Nov 2017
  162. elifesciences.org elifesciences.org
    Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring
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  163. www.jbc.org www.jbc.org
    Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a
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