This all occurs in the viroplasm, which is a highly organized large cytoplasmic inclusion body that serves as a viral factory to direct the packaging and replication of the viral genome into early capsid assembly intermediates (Lopez, Patton).

Once at the cell body, however, replication and transcription are believed to occur in Negri bodies (2). Negri bodies are cytoplasmic inclusion bodies which are aggregates mainly composed of protein within the cytoplasm (2) (13)