- Jun 2017
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sites.google.com sites.google.com
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This all occurs in the viroplasm, which is a highly organized large cytoplasmic inclusion body that serves as a viral factory to direct the packaging and replication of the viral genome into early capsid assembly intermediates (Lopez, Patton).
Both rotavirus and the rabies virus are RNA viruses that are replicated by a protein structure in the cytoplasm.
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sites.google.com sites.google.com
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Once at the cell body, however, replication and transcription are believed to occur in Negri bodies (2). Negri bodies are cytoplasmic inclusion bodies which are aggregates mainly composed of protein within the cytoplasm (2) (13)
Both rotavirus and the rabies virus are RNA viruses that are replicated by a protein structure in the cytoplasm.
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Purple circles attached to the rabies virus membrane (red) represent the glycoproteins which can bind to the clathrin molecules (navy colored Y's) in the clathrin-coated pit. From there a decrease in pH triggers endocytosis of the virus.
Both Rotavirus and the Rabies virus enter the host cell through endocytosis.
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- May 2017
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Using Kirby–Bauer method, it was sensitive to cefazoline, chloramphenicol, ciprofloxacin, gatifloxacin, moxifloxacin and ofloxacin.
antibiotics
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Published literature on S. putrefaciens, has reported sensitivity to aminoglycosides, fluoroquinolones, third/fourth-generation cephalosporins, and resistance to penicillin.
antibiotics
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www.sigmaaldrich.com www.sigmaaldrich.com
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On the Trail of Campylobacter
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Tables 2 and 3.
more testing
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Allculturesgrewat43°Candnotat25°C,werecatalaseandoxidasepositive,didnotproduceH2Sontriplesugar-ironmedia,wereresistanttocephalothin,anddidnotgrowaerobically.Previouslyfrozenorlyophilizedculturesw
tests
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cmr.asm.org cmr.asm.org
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Laboratory Diagnosis of Bacterial Gastroenteritis
Great resource with all (?) the organisms in our case
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Nosocomial outbreaks of infection due to non-typeable Haemophilus influenzae (NTHi) are rarely described. There are a few published reports that suggest that elderly patients with underlying pulmonary disease are at risk and that person-to-person spread is key to disease transmission. During the summer months of 2005, we documented an outbreak of NTHi infections in a Veterans Affairs nursing home. Thirteen patients developed conjunctivitis or lower respiratory infection involving a beta-lactamase-negative biotype III NTHi isolate, with an indistinguishable SmaI macrorestriction pattern. Patients were elderly males usually with underlying cardiac and pulmonary disease.
H. influenzae causing outbreaks is rare but possible
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academic.oup.com academic.oup.com
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penicillin 96 0 4 ≤0.06–8 ≤0.06 ≤0.06 amoxicillin/clavulanic acid 100 0 0 ≤0.06–0.25 ≤0.06 0.12 piperacillin/tazobactam 100 0 0 ≤0.12–≤0.12 ≤0.12 ≤0.12 cefoxitin 100 0 0 ≤0.12–1 ≤0.12 ≤0.12 cefotetan 100 0 0 ≤0.12–4 ≤0.12 ≤0.12 ceftriaxone 100 0 0 ≤0.12–4 ≤0.12 ≤0.12 clindamycin 100 0 0 ≤0.06–≤0.06 ≤0.06 ≤0.06 imipenem 100 0 0 ≤0.06–0.12 ≤0.06 ≤0.06 meropenem 100 0 0 ≤0.06–≤0.06 ≤0.06 ≤0.06 metronidazole 100 0 0 ≤0.06–0.5 0.12 0.25
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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While penicillins remain the treatment of choice in most cases of LS, cephalosporins (such as cefoxitin and cefotetan), metronidazole, or clindamycin monotherapy can sometimes be used as first-line drugs owing to the rare emergence of penicillin-resistant strains with β-lactamase activity.11
cephalos work with f necro
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en.wikipedia.org en.wikipedia.org
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In the lungs, the bacteria cause abscesses, nodulary and cavitary lesions. Pleural effusion is often present
long term effects?
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Lemierre's syndrome begins with an infection of the head and neck region. Usually this infection is a pharyngitis (which occurred in 87.1% of patients as reported by a literature review[5]), but it can also be initiated by infections of the ear, mastoid bone, sinuses, or saliva glands. During the primary infection, F. necrophorum colonizes the infection site and the infection spreads to the parapharyngeal space.
In the case she had "strep throat" which made her vulnerable to infection with our bug
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swollen cervical lymph nodes,
a symptom of our case
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www.webmd.com www.webmd.com
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The uvula (the small finger of tissue that hangs down in the middle of the throat) may be shoved away from the swollen side of the mouth.
A symtom of abscess formation, a symtom of Lumieres
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Streptococcal bacteria most commonly cause an infection in the soft tissue around the tonsils (usually just on one side). The tissue is then invaded by anaerobes (bacteria that can live without oxygen), which enter through nearby glands.
A possible progression from strep to lumieres which is relevant to the case
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Among a total of 248 samples, 27 were positive for beta-haemolytic streptococcus group A, two were positive for beta-haemolytic streptococcus group C, five were positive for beta-haemolytic streptococcus group G and 24 were positive for F. necrophorum. The most common isolate in the under 20 age group was beta-haemolytic streptococcus group A. In the over 20 age group, F. necrophorum was the pathogen most frequently isolated. A clinical diagnosis of 'sore throat' was most likely to be positive for beta-haemolytic streptococcus group A, a clinical diagnosis of PSTS was most likely to be positive for F. necrophorum and a clinical diagnosis of 'tonsillitis' was equally likely to be caused by beta-haemolytic streptococcus group A or F. necrophorum. beta-haemolytic streptococcus group A was present in 11% of the samples and F. necrophorum was present in 10% of the samples. In total, these two pathogens accounted for 18.5% of throat infections in the sampled group. The results show that F. necrophorum is as significant a cause of throat infection as is beta-haemolytic streptococcus group A.
prevalence data
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www.idpublications.com www.idpublications.com
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metastatic abscesses are always present and that these weremost often in the lungs.
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- Apr 2017
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microbewiki.kenyon.edu microbewiki.kenyon.edu
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Staphylococci are spherical gram-positive bacteria, which are immobile and form grape-like clusters. They form bunches because they divide in two planes as opposed to their close relatives streptococci which form chains because they divide only in one plane.
A way to distinguish from strep
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www.fidanoski.ca www.fidanoski.ca
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Beta hemolytic
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www.cnn.com www.cnn.com
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There are rare examples of when we do see that happen, like in the Ebola outbreak, because we followed it in real time, but when you try to reconstruct after the fact, it's easy to be misled."
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